透明质酸注射联合咀嚼肌功能训练治疗老年性颞下颌关节骨关节炎患者的临床研究

doi:10.13701/j.cnki.kqyxyj.2019.03.017

口腔医学研究 ›› 2019, Vol. 35 ›› Issue (3): 262-265.DOI: 10.13701/j.cnki.kqyxyj.2019.03.017

透明质酸注射联合咀嚼肌功能训练治疗老年性颞下颌关节骨关节炎患者的临床研究

蔡恒星^*, 柯金, 孟庆功, 龙星

武汉大学口腔医学院口腔颌面外科湖北武汉 430079

收稿日期:2019-01-25 出版日期:2019-03-28 发布日期:2019-04-01
通讯作者: * 蔡恒星,电话:027-87686216
作者简介:蔡恒星(1974~ ),男,河南周口人,博士,副教授,副主任医师,主要从事口腔颌面外科临床及基础的研究工作。

Effects of Hyaluronic Acid Injection Combined with Masticatory Muscle Exercise on Geriatric Temporomandibular Joint Osteoarthrosis

CAI Heng-xing^*, KE Jin, MENG Qing-gong, LONG Xing

School of Stomatology, Wuhan University, Wuhan 430079, China.

Received:2019-01-25 Online:2019-03-28 Published:2019-04-01

摘要/Abstract

摘要： 目的:探讨透明质酸关节腔注射联合咀嚼肌功能训练在老年性颞下颌关节骨关节炎患者治疗中的作用及意义。方法:在武汉大学口腔医院颞下颌关节专科就诊的老年患者,经临床检查和影像学检查确诊为颞下颌关节骨关节炎后随机分为2组,实验组30人,对照组30人。对照组采用咀嚼肌功能训练进行治疗,实验组采用透明质酸关节腔注射治疗联合咀嚼肌功能训练的方法进行治疗,所有患者在治疗完成后3月、6月进行复诊,每次就诊时记录患者的关节疼痛(视觉模拟评分法,visual analog scale,VAS),最大张口度(maximal mouth opening,MMO)和关节杂音(joint noise, JN),对结果进行统计学分析。结果:治疗效果方面,关节腔注射未见明显并发症,实验组和对照组VAS和MMO较治疗前均有好转,实验组JD较治疗前好转,差异具有统计学意义(P<0.05),对照组治疗前后关节杂音没有差异(P>0.05)。实验组和对照组相比,VAS、MMO、JN均有显著性改善(P<0.05)。结论:采用透明质酸关节腔注射联合咀嚼肌功能训练治疗老年性颞下颌关节骨关节炎患者,临床应用安全,能改善患者的临床症状,治疗效果优于单纯的咀嚼肌功能训练。

关键词: 老年人, 颞下颌关节, 骨关节病, 透明质酸, 咀嚼肌功能训练

Abstract: Objective: To observe the effects of hyaluronic acid (HA) injection combined with masticatory muscle exercise on geriatric temporomandibular joint osteoarthrosis. Methods: The subjects were recruited from Stomatological Hospital of Wuhan University. After clinical and X-ray examination, 60 patients were divided into the experimental group and the control group. The experimental group received intra-articular injection of HA in combination with masticatory muscle exercise, and the control group received the masticatory muscle exercise only. The subjects were followed after 3 months and 6months. Clinical parameters such as joint pain (VAS), maximal mouth opening (MMO), and joint noise (JN) were recorded at each visit. Comparative analysis was then performed. Results: No serious complications were observed in the treatment process. After treatment, there were significant improvements in the VAS and MMO in the experimental group and control group, and improvement in the JN in the control group (P<0.05). There was significant improvement for all the clinical scores in the experimental group compared with the control group (P<0.05). Conclusion: Intra-articular injection of HA combined with masticatory muscle exercise is a safe, effective method in the treatment of geriatric temporomandibular joint osteoarthrosis, which is better than masticatory muscle exercise only.

Key words: The aged, Temporomandibular joint, Osteoarthrosis, Hyaluronic acid, Masticatory muscle exercise

蔡恒星, 柯金, 孟庆功, 龙星. 透明质酸注射联合咀嚼肌功能训练治疗老年性颞下颌关节骨关节炎患者的临床研究[J]. 口腔医学研究, 2019, 35(3): 262-265.

CAI Heng-xing, KE Jin, MENG Qing-gong, LONG Xing. Effects of Hyaluronic Acid Injection Combined with Masticatory Muscle Exercise on Geriatric Temporomandibular Joint Osteoarthrosis[J]. Journal of Oral Science Research, 2019, 35(3): 262-265.

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透明质酸注射联合咀嚼肌功能训练治疗老年性颞下颌关节骨关节炎患者的临床研究

Effects of Hyaluronic Acid Injection Combined with Masticatory Muscle Exercise on Geriatric Temporomandibular Joint Osteoarthrosis

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