较大载荷下加载时机对正畸微种植钉骨结合的影响

doi:10.13701/j.cnki.kqyxyj.2019.05.016

口腔医学研究 ›› 2019, Vol. 35 ›› Issue (5): 480-482.DOI: 10.13701/j.cnki.kqyxyj.2019.05.016

较大载荷下加载时机对正畸微种植钉骨结合的影响

丘雨蓓, 郭伟忠, 陈江^*

福建医科大学附属口腔医院福建医科大学口腔医学院福建福州 350004

收稿日期:2018-10-01 出版日期:2019-05-28 发布日期:2019-05-21
通讯作者: 陈江,E-mail:dentistjiangch@sina.com
作者简介:丘雨蓓(1982~ ),女,福建人,主治医师,硕士,主要从事口腔正畸及材料学相关研究。
基金资助:
福建省教育厅青年教师教育科研项目(编号:JA14149)

Effect of Different Loading Time on Osseointegration between Mini-implant and Bone under Large Loading Force.

QIU Yu-bei, GUO Wei-zhong, CHEN Jiang^*

School and Hospital of Stomatology, Fujian Medical University, Fuzhou 350004, China.

Received:2018-10-01 Online:2019-05-28 Published:2019-05-21

摘要/Abstract

摘要： 目的: 探讨在较大载荷情况下,不同加载时机对微种植钉-骨组织界面骨结合的影响。方法: 将32枚微种植钉植入8只成年雄性Beagle犬下颌骨,分别于植入后即刻、2周、4周及8周后加载350g的力值。加载4周后处死实验动物并取材,检测各组微种植钉旋出扭力峰值及在光学显微镜下观察微种植体-骨组织界面的形态。结果: 除即刻加力组有1颗微种植体有轻微松动,植入2周后加力组2枚微种植钉脱落外,其余所有微种植体均没有松动、脱落。植入8周后加载组的旋出扭力峰值大于植入4周后加载组(P=0.03),微种植体-骨组织界面为成熟的骨组织,而植入4周后加载组骨界面可见与旧骨分界明显的新骨。即刻加载组和植入2周后加载组的旋出扭力峰值最低,且两组之间差异无统计学意义(P=0.78),微种植体与骨组织之间均存在纤维结缔组织,植入2周后加载组更为明显。结论: 在较大的载荷下,微种植钉植入后即刻加载及植入2周后加载均存在一定的风险,若想要获得更高的稳固性,建议植入4周以后再开始加载。

关键词: 较大载荷, 加载时机, 微种植体, 骨结合

Abstract: Objective: To investigate the effect of different loading time on the osseointegration between mini-implant and bone under large loading force. Methods: Twenty-four mini-implants were implanted into the mandibles of six beagle dogs. 350g force was loaded onto the corresponding mini-implants immediately (0 w group), 2 weeks (2w group), 4 weeks (4w group), and 8 weeks (8w group) after implantation. Maximum removal torque (MRT) was tested and histology of the interface of implant-bone tissue was observed using HE staining after 4 weeks of loading. Results: Two of the mini-implants in 2w group were lost and 1 in 0w group was unstable. Other mini-implants were stable. The MRT of the 8w group was higher than that of 4w group (P=0.03). The interface of mini-implant-bone tissue in 8w group was composed of mature bone tissue, while it was composed of newly formed bone in 4w group. The lowest MRT was detected from the 0w group and 2w group, and no significant difference was found between these two groups (P=0.78). Furthermore, more obvious fibrous tissue was observed in the 2w group in contrast to 0w group. Conclusion: Some risks may occur if loaded immediately or 2 weeks after implantation. It is suggested to load 4 weeks later after implantation.

Key words: Large loading force, Loading time, Mini-implant, Osseointegration

丘雨蓓, 郭伟忠, 陈江. 较大载荷下加载时机对正畸微种植钉骨结合的影响[J]. 口腔医学研究, 2019, 35(5): 480-482.

QIU Yu-bei, GUO Wei-zhong, CHEN Jiang. Effect of Different Loading Time on Osseointegration between Mini-implant and Bone under Large Loading Force.[J]. Journal of Oral Science Research, 2019, 35(5): 480-482.

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较大载荷下加载时机对正畸微种植钉骨结合的影响

Effect of Different Loading Time on Osseointegration between Mini-implant and Bone under Large Loading Force.

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