口腔医学研究 ›› 2023, Vol. 39 ›› Issue (3): 193-196.DOI: 10.13701/j.cnki.kqyxyj.2023.03.002

• 综述 • 上一篇    下一篇

地塞米松在牙髓病学中的研究进展

刘晓莉1,2, 李毅1,2*   

  1. 1.吉林大学口腔医院儿童口腔科 吉林 长春 130012;
    2.吉林省牙发育及颌骨重塑与再生重点实验室 吉林 长春 130012
  • 收稿日期:2022-04-06 出版日期:2023-03-28 发布日期:2023-03-21
  • 通讯作者: * 李毅,E-mail:lyi99@jlu.edu.cn
  • 作者简介:刘晓莉(1997~ ),女,四川内江人,硕士在读,主要从事牙髓病学研究。
  • 基金资助:
    吉林省财政厅科研项目(编号:jsz2018170-16);吉林省卫生健康科技能力提升项目(编号:2019J034)

Application of Dexamethasone in Dental Pulp Diseases

LIU Xiaoli1,2, LI Yi1,2*   

  1. 1. Department of Pediatric Dentistry, Hospital of Stomatology, Jilin University, Changchun 130012, China;
    2. Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130012, China
  • Received:2022-04-06 Online:2023-03-28 Published:2023-03-21

摘要: 牙髓疾病是口腔中常见的疾病,机械、化学、微生物和热因素等会刺激牙髓触发炎症免疫反应,引起牙髓血管扩张、免疫细胞聚集,最终导致组织损伤。地塞米松作为糖皮质激素,因具有抗炎、成骨及镇痛作用,在牙髓病学中的应用越来越广泛,在根管治疗、活髓保存术等领域具有较好的应用前景。本文总结了地塞米松在牙髓疾病中的作用机制及应用。

关键词: 地塞米松, 根管治疗, 盖髓, 活髓保存, 口腔医学

Abstract: Dental pulp disease is a common disease in oral cavity. Mechanical, chemical, microbial, and thermal factors will stimulate dental pulp, trigger inflammatory immune response, cause dental pulp vascular dilatation and immune cell aggregation, and finally lead to tissue damage. As a glucocorticoid, dexamethasone is more and more widely used in endodontics because of its anti-inflammatory, osteogenic, and analgesic effects. It has a better practical perspective in the fields of root canal therapy, vital pulp preservation, and so on. This paper summarizes the mechanism and application of dexamethasone in dental pulp diseases.

Key words: dexamethasone, root canal therapy, pulp capping, preservation of living pulp, stomatology