口腔医学研究 ›› 2022, Vol. 38 ›› Issue (1): 9-12.DOI: 10.13701/j.cnki.kqyxyj.2022.01.002

• 综述 • 上一篇    下一篇

智能生物材料在口腔领域中的应用

何彦瑾, 陈文川*   

  1. 口腔疾病研究国家重点实验室;
    国家口腔疾病临床医学研究中心;
    四川大学华西口腔医院修复1科 四川 成都 610041
  • 收稿日期:2021-07-13 出版日期:2022-01-28 发布日期:2022-01-21
  • 通讯作者: * 陈文川,E-mail:hxkqcwc@scu.edu.cn
  • 作者简介:何彦瑾(1996~ ),女,四川成都人,硕士在读,主要从事骨组织工程相关研究。
  • 基金资助:
    国家自然科学基金面上项目(编号:81771049)

Application of Smart Biomaterials in Dentistry

HE Yanjin, CHEN Wenchuan*   

  1. State Key Laboratory of Oral Diseases;
    National Clinical Research Center for Oral Diseases;
    Department of Prosthodontics 1, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2021-07-13 Online:2022-01-28 Published:2022-01-21

摘要: 生物医用材料是一类用于修复或替换病损组织和器官,或增进其功能的生物功能性材料。近年来,在材料学、材料制造学、分子细胞生物学等多学科的协同发展下,生物医用材料的研究和应用取得了巨大的进步。智能生物材料是能感知和响应外部刺激的新一代生物材料。与以往的生物材料相比,它更强调材料与组织之前的相互作用和动态调控。智能生物材料因其良好的组织反应性,在药物靶向递送载体和组织工程支架等口腔医学领域中表现出了优良的性能和疗效。本文就生物医用材料的发展历程及智能生物材料在口腔医学领域中的研究现状进行综述,以推动其在口腔医学领域中的研究和临床应用。

关键词: 智能生物材料, 口腔医学, 药物递送, 组织工程

Abstract: Biomedical materials are biofunctional materials used to repair or replace damaged tissues and organs, or to enhance their functions. With the collaborative development of materials science, materials manufacturing science, molecular cell biology, and other disciplines, the research and application of biomedical materials have made great progress. The smart biomaterials are a new generation of biomaterials that can sense and respond to external stimuli. Compared with the previous biomaterials, they emphasize the interaction and dynamic regulation between materials and tissues. The smart biomaterials show excellent performance and efficacy in dentistry such as targeted drug delivery carriers and tissue engineering scaffolds because of their good tissue reaction. This article reviews the development of biomedical materials and the research progress of smart biomaterials in dentistry, aiming to promote their research and clinical application in dentistry.

Key words: smart biomaterial, dentistry, drug delivery, tissue engineering