硅酸镁锂在生物医学领域的研究进展及应用

doi:10.13701/j.cnki.kqyxyj.2021.04.004

摘要/Abstract

摘要： 通过人工方法合成的硅酸镁锂无机材料具有纳米级的2D结构,其优良的理化性能和丰富的电化学特性,已被广泛应用于日化、食品、卫生材料领域;其良好的生物相容性、一定的抗菌性以及在促进干细胞增殖和分化方面的生物学效应,使其拥有在生物医学领域应用的潜力。本文主要综述硅酸镁锂在生物医学领域的研究进展:对药物分子、蛋白质、生长因子的递载;皮肤黏膜的屏障保护作用;用于组织工程中合成支架材料、调控干细胞增殖分化等,并展望其在口腔医学领域的应用前景。

关键词: 硅酸镁锂, 纳米复合物, 组织工程, 成骨分化

Abstract: Nanosilicates inorganic material synthesized by artificial methods has a nano-scale 2D structure. Its excellent physical and chemical properties as well as rich electrochemical characteristics have been widely used in the field of daily chemical, food, and sanitary materials. The good biocompatibility, certain antibacterial properties, and promotion of stem cell proliferation and differentiation have made it a potential to be applied in the field of biomedicine. This article mainly reviews the research progress of synthetic nanosilicates in biomedicine, the delivery of drug molecules, proteins, and growth factors, protection of skin and mucous membrane as a barrier, and as synthesize scaffold materials to regulate stem cell proliferation and differentiation in tissue engineering. Finally, the paper looks forward to the application of nanosilicates in the stomatology.

Key words: synthetic nanosilicates, nanocomposite, tissue engineering, osteogenic differentiation

王明霞, 刘志辉. 硅酸镁锂在生物医学领域的研究进展及应用[J]. 口腔医学研究, 2021, 37(4): 292-295.

WANG Mingxia, LIU Zhihui. Research Progress and Application of Synthetic Nanosilicates in Biomedical Field[J]. Journal of Oral Science Research, 2021, 37(4): 292-295.

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