引导骨组织再生膜的研究进展

doi:10.13701/j.cnki.kqyxyj.2016.03.024

口腔医学研究 ›› 2016, Vol. 32 ›› Issue (3): 308-310.DOI: 10.13701/j.cnki.kqyxyj.2016.03.024

引导骨组织再生膜的研究进展

马士卿, 张旭, 孙迎春, 高平

天津医科大学口腔医学院天津 300070

收稿日期:2014-12-01 出版日期:2016-03-28 发布日期:2016-03-29
通讯作者: 高平，E-mail:gptj@sina.com
作者简介:马士卿(1991~ ),女,山东人,博士在读,主要从事口腔修复相关临床及基础的研究工作。
基金资助:
国家自然科学基金资助项目(编号:31470919)
国家级大学生创新创业计划训练项目(编号:201310062005)
天津市应用基础及前沿技术研究计划资助项目(编号:14JCYBJC29600)

Research Progress of GBR Membrane.

MA Shi-qing, ZHANG Xu, SUN Ying-chun, GAO Ping^*

School of stomatology, Tianjin Medical University. Tianjin 300070, China.

Received:2014-12-01 Online:2016-03-28 Published:2016-03-29

摘要/Abstract

摘要： 引导骨组织再生术(guided bone regeneration, GBR)是目前促进骨组织再生的有效手段,而GBR膜是决定其临床效果的主要因素之一,也是该领域的重点关注内容。GBR膜在骨组织再生中不仅具着物理性屏障膜的作用,同时还能起到保护局部血块、聚集骨诱导因子、进行骨传导等作用。本文将对膜引导骨组织再生的机理、GBR膜的制备技术及分类、GBR膜的发展趋势等方面进行论述。

关键词: 引导骨组织再生, 膜, 进展

Abstract: Guided bone regeneration (GBR) is an effective therapy to promote bone regeneration. GBR membrane, the central issue of GBR field, is one of the main factors to determine the clinical effect. In bone tissue regeneration, GBR membrane not only plays the effect of a physical barrier membrane, but also can protect local blood clots, aggregate bone factors and conduct bone tissue. This article discussed the mechanism of membrane guided bone regeneration, the preparation and classification of GBR membrane and the development trend of the GBR membrane.

Key words: GBR , Membrane , Progress

中图分类号:

R782.2

马士卿, 张旭, 孙迎春, 高平. 引导骨组织再生膜的研究进展[J]. 口腔医学研究, 2016, 32(3): 308-310.

MA Shi-qing, ZHANG Xu, SUN Ying-chun, GAO Ping. Research Progress of GBR Membrane.[J]. Journal of Oral Science Research, 2016, 32(3): 308-310.

参考文献

[1] Neel EAA, Chrzanowski W, Salih VM, et al. Tissue engineering in dentistry [J]. Journal of Dentistry,2014,42(8)∶915-28
[2] Scantlebury TV. 1982-1992: A decade of technology development for guided tissue regeneration [J]. J Periodont,1993,64(11s)∶1129-37
[3] Chen FM, Zhang J, Zhang M, et al. A review on endogenous regenerative technology in periodontal regenerative medicine [J]. Biomaterials,2010,31(31)∶7892-927
[4] Moura JML, Ferreira JF, Marques L, et al. Comparison of the performance of natural latex membranes prepared with different procedures and PTFE membrane in guided bone regeneration (GBR) in rabbits [J]. Journal of Materials Science: Materials in Medicine,2014,25(9)∶2111-20
[5] Kanczler J, Oreffo R. Osteogenesis and angiogenesis: the potential for engineering bone [J]. Eur Cells Mater,2008,15(2)∶100-14
[6] Brandi ML, Collin-Osdoby P. Vascular biology and the skeleton [J]. J Bone Miner Res,2006,21(2)∶183-92
[7] Kim TH, Oh SH, Na SY, et al. Effect of biological/physical stimulation on guided bone regeneration through asymmetrically porous membrane [J]. Journal of Biomedical Materials Research Part A,2012,100(6)∶1512-20
[8] Park YJ, Nam KH, Ha SJ, et al. Porous poly(L-lactide) membranes for guided tissue regeneration and controlled drug delivery: membrane fabrication and characterization [J]. Journal of controlled release,1997,43(2)∶151-60
[9] Mi FL, Wu YB, Shyu SS, et al. Asymmetric chitosan membranes prepared by dry/ wet phase separation a new type of wound dressing for controlled antibacterial release [J]. Journal of Membrane Science,2003,212(1)∶237-54
[10] Deng A, Chen A, Wang S, et al. Porous nanostructured poly-l-lactide scaffolds prepared by phase inversion using supercritical CO₂ as a nonsolvent in the presence of ammonium bicarbonate particles [J]. The Journal of Supercritical Fluids, 2013, 77∶110-6
[11] Tsivintzelis I, Pavlidou E, Panayiotou C. Porous scaffolds prepared by phase inversion using supercritical CO₂ as antisolvent [J]. The Journal of Supercritical Fluids, 2007, 40(2)∶317-22
[12] Holzwarth JM, Ma PX. Biomimetic nanofibrous scaffolds for bone tissue engineering [J]. Biomaterials, 2011, 32(36)∶9622-9
[13] Chen KY, Liao WJ, Kuo SM, et al. Asymmetric Chitosan Membrane Containing Collagen I Nanospheres for Skin Tissue Engineering [J]. Biomacromolecules, 2009, 10(6)∶1642-9
[14] Hong H, Wei J, Liu C. Development of asymmetric gradational-changed porous chitosan membrane for guided periodontal tissue regeneration [J]. Composites Part B: Engineering, 2007, 38(3)∶311-6
[15] Jaiswal A, Kadam S, Soni V, et al. Fabrication of biocomposite membrane by electrospinning for guided bone regeneration [J]. Tissue Engineering Part A, 2011, 17(3-4)∶561-2
[16] Hardwick R, Hayes BK, Flynn C. DEVICES FOR DENTOALVEOLAR REGENERATION - AN UP-TO-DATE LITERATURE-REVIEW [J]. Journal of periodontology, 1995, 66(6)∶495-505
[17] 韩舒,杨军星,宋志光,等.藻酸盐缓释微球的研究进展[J].口腔医学研究,2014,30(11)∶1107-9
[18] Sohn JO, Park EK, Lee JH, et al. Evaluation of the Hydrophilized Asymmetric Pore Sized Polydioxanone Membrane for Guided Bone Regeneration [J]. Tissue Engineering and Regenerative Medicine, 2012, 9(1)∶A1-A8
[19] Tai HY, Fu E, Cheng LP, et al. Fabrication of asymmetric membranes from polyhydroxybutyrate and biphasic calcium phosphate/chitosan for guided bone regeneration [J]. Journal of Polymer Research,2014,21(5)∶1-11
[20] 韩爽杨学文. 牵张成骨中生长因子的研究进展[J].口腔医学研究,2014,30(4)∶378-80
[21] Murakami S, Takayama S, Ikezawa K, et al. Regeneration of periodontal tissues by basic fibroblast growth factor [J]. J Periodontal Res,1999,34(7)∶425-30
[22] Jung MR, Shim IK, Chung HJ, et al. Local BMP-7 release from a PLGA scaffolding-matrix for the repair of osteochondral defects in rabbits [J]. Journal of Controlled Release,2012,162(3)∶485-91
[23] Chang PC, Dovban AS, Lim LP, et al. Dual delivery of PDGF and simvastatin to accelerate periodontal regeneration in vivo [J]. Biomaterials,2013,34(38)∶9990-7
[24] Liu X, Ma L, Mao Z, et al. Chitosan-Based Biomaterials for Tissue Repair and Regeneration [J]. Advances in Polymer Science, 2011∶81-127
[25] Martins A, Duarte ARC, Faria S, et al. Osteogenic induction of hBMSCs by electrospun scaffolds with dexamethasone release functionality [J]. Biomaterials, 2010, 31(22)∶5875-85
[26] Norowski PA, Babu J, Adatrow PC, et al. Antimicrobial activity of minocycline-loaded genipin-crosslinked nano-fibrous chitosan mats for GTR [J]. Journal of Biomaterials and Nanobiotechnology, 2012, 3(4A)∶528

引导骨组织再生膜的研究进展

Research Progress of GBR Membrane.

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

[1]	朱肖雪, 赵苏峰, 杨旭东, 孙国文, 杨亚萍, 黄丽娟, 何凯. 计算机辅助设计联合3D打印应用于自体牙移植[J]. 口腔医学研究, 2021, 37(1): 76-80.
[2]	刘悦, 王雷. 他汀类药物与牙周炎关系的研究进展[J]. 口腔医学研究, 2020, 36(9): 811-813.
[3]	程璐, 史剑杰. 骨膜减张技术在引导骨再生术中的应用研究进展[J]. 口腔医学研究, 2020, 36(9): 814-816.
[4]	周何洁, 李胜鸿, 彭培钊, 唐榕, 李艾莲, 曾锦. “红色复合体”致病菌裂解液对人牙周膜细胞成骨分化能力的影响[J]. 口腔医学研究, 2020, 36(9): 839-843.
[5]	邱吟枫, 汤颖, 沈忆芬, 刘超, 沈昊, 顾永春, 于金华. 氟暴露对人牙周膜干细胞增殖及成骨分化的影响[J]. 口腔医学研究, 2020, 36(9): 866-870.
[6]	赵霞, 徐嘉昊, 夏商, 张晨, 王万春. Farnesol纳米胶束的构建及对变形链球菌的抑菌作用研究[J]. 口腔医学研究, 2020, 36(9): 875-878.
[7]	王琳璇, 王琦, 赵云, 刘一鸣, 韩梅, 米方林. TNF-α对牙周膜成纤维细胞ephrinB2/EphB4表达量的影响[J]. 口腔医学研究, 2020, 36(8): 741-744.
[8]	张旭阳, 李慧, 刘漪, 娄亭亭, 鲍雪滢, 李诗雅, 黄辉. 乳酸链球菌素对粪肠球菌生物膜的清除作用[J]. 口腔医学研究, 2020, 36(7): 635-638.
[9]	张慧彦, 李保胜, 张震阳, 韩春雨, 李尊泰, 齐晓爽, 付齐月, 孟维艳. D/L-缬氨酸对牙龈卟啉单胞菌及其生物膜的作用[J]. 口腔医学研究, 2020, 36(7): 648-653.
[10]	刘芳芳, 邱忠营, 王艳丽. EBV LMP1对牙龈上皮细胞促炎因子的调控及机制研究[J]. 口腔医学研究, 2020, 36(7): 654-657.
[11]	邬扬绚, 向黎, 黄志强, 褚金海. 釉基质蛋白衍生物调节牙龈卟啉单胞菌感染牙周膜干细胞成骨分化的作用及机制[J]. 口腔医学研究, 2020, 36(6): 534-538.
[12]	苏涛, 王星星, 向彪, 吴刚, 邹敏. 不同刚度的无托槽隐形矫治器扩大上颌牙弓的有限元分析[J]. 口腔医学研究, 2020, 36(5): 454-458.
[13]	王薛藤, 聂敏海, 左东川, 邓浩, 曾锦. TRPM4通道对人口腔颊黏膜成纤维细胞增殖和迁移的影响[J]. 口腔医学研究, 2020, 36(5): 490-495.
[14]	朱德超, 卢海燕. 下颌前移矫治器治疗成人阻塞性睡眠呼吸暂停低通气综合征的研究进展[J]. 口腔医学研究, 2020, 36(4): 324-327.
[15]	田源, 陈靖, 曾凤娇, 于航, 刘霞, 刘建国, 白国辉. SD大鼠经鼻黏膜免疫牙周炎基因疫苗pVAX1-HA2-FimA-(IL-15)后Tfh细胞的变化[J]. 口腔医学研究, 2020, 36(4): 350-354.