Abstract: Objective: To improve the level of clinical diagnosis and treatment by retrospective analyzing the clinical cases of solitary fibrous tumor in oral and maxillofacial region. Methods: A retrospective analysis was conducted on the maxillofacial solitary fibroma, which was included in the pathological database of Nanjing Stomatological Hospital affiliated to Nanjing University from June 2015 to June 2019. The clinical data, imaging data, pathological data, treatment methods, and follow-up data of the patients were analyzed. Results: A total of 8 patients were diagnosed as solitary fibrous tumor in oral and maxillofacial region by postoperative pathology. Of the 2 patients whose postoperative pathology was low grade malignant tumor, 1 had recurrence in other hospital, but no recurrence was found in our hospital at present, and 1 patient had recurrence in postoperative follow-up. Conclusion: Complete resection is the first choice for the treatment of solitary fibroma of maxillofacial region. When it is found that solitary fibroma of the maxillofacial area is prone to soft tissue masses and the imaging enhancement is obvious, the possibility of solitary fibroma should be considered, and the final diagnosis should rely on pathological and immunohistochemical examination. Clinically, patients should be alerted to the invasive or malignant solitary fibroma of the maxillofacial region. Patients should be followed up closely after surgery, and timely surgery should be carried out if recurrence exists.

Key words: oral and maxillofacial tumor, solitary fibrous tumor, surgical procedures, retrospective analysis