Journal of Oral Science Research

Journal of Oral Science Research ›› 2024, Vol. 40 ›› Issue (10): 938-940.DOI: 10.13701/j.cnki.kqyxyj.2024.10.018

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Nodule on Lower Lip Presented as First Sign of Syphilis: A Case Report

WANG Fang1,2, SU Zhuizi1,3, ZHOU Gang1,3*   

  1. 1. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China;
    2. Center for Cariology, Endodontics and Periodontics, Optics Valley Branch, School & Hospital of Stomatology, Wuhan University, Wuhan 430074, China;
    3. Department of Oral Medicine, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2024-08-26 Online:2024-10-28 Published:2024-10-24

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Abstract: Syphilis is an infectious disease mainly transmitted through sexual contact. The oral damage of early syphilis is varied, which is easy to be misdiagnosed. Penicillin is the first choice for the treatment of syphilis, but some patients have allergic reactions or other problems, which puts a lot of limitations on the use of it. This article reports a case of syphilis with a nodule as the first sign on the lower lip with penicillin allergy and, who was treated by doxycycline with good effect, aiming to emphasize early detection, diagnosis and treatment of syphilis.

Key words: syphilis, chancre, penicillin, doxycycline