Abstract: Fungal osteomyelitis in the oral and maxillofacial region is extremely rare in clinical, whose diagnosis is very difficult. Due to the lack of characteristic clinical manifestations and test results, it often leads to misdiagnosis, delays treatment, and even endangers life. This paper reports the combined diagnosis and treatment of a case of maxillary osteomyelitis caused by fungal infection. The etiology, clinical manifestations, diagnosis, and treatment plan were discussed.

Key words: maxilla, osteomyelitis, fungal infection, combination therapy