Clinical Study of Gorham Disease in Maxillofacial Region.

doi:10.13701/j.cnki.kqyxyj.2017.12.018

Abstract

Abstract: Objective: To investigate the clinical features, imaging examination and treatment of the patients with Gorham disease in maxillofacial region. Methods: The medical records of the patients with Gorham Disease who were referred to Shanghai Ninth People's Hospital from January 2010 to 2016 May were reviewed. Their ages, lesion location, imaging results, laboratory examination results, and treatment and therapeutic effects were analyzed. Results: A total of 4 cases were included (2 male and 2 female). The average onset age was 40 year olds. Gorham disease attacked the mandible in 2 cases, and mandible and temporal bone in other 2 cases. All cases were examined by CT, which showed bone resorption and atrophy of soft tissue. Four patients were given alendronate to treat Gorham disease. All of them had not significant bone resorption after the treatment. Conclusion: Gorham disease can affect any maxillofacial bone, whether single bone or multiple bones. The patients are mostly young and middle-aged. The diagnosis mainly depends on the imaging methods and the laboratory examination has not special meaning. Alendronate can be used and the effect is certain.

Key words: Gorham disease, Mandibular, Imaging examination, Alendronate

CLC Number:

R782.2

QU Lu-yao, CAI Xie-yi.. Clinical Study of Gorham Disease in Maxillofacial Region.[J]. Journal of Oral Science Research, 2017, 33(12): 1310-1313.

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