Effect of Root Canal Therapy on Bacterial Colonization of Periodontal-derived Combined Periodontal and Endodontic Lesions

doi:10.13701/j.cnki.kqyxyj.2021.09.013

Abstract

Abstract: Objective: To explore the effect of root canal treatment on the prognosis of combined periodontal and endodontic lesions of periodontal origin, according to the difference of periodontal microorganisms. Methods: From 2018 to 2020, 31 cases of periodontal-derived combined periodontal and endodontic lesions with retrograde pulpitis and root canal treatment were collected from the People’s Hospital of Xinjiang Uygur Autonomous Region. Clinical samples were collected from the root canal and periodontal pocket before and after root canal treatment. DNA was extracted from the samples and respectively detected 8 suspected pathogenic microorganisms through qRT-PCR, including T.forsythensis, P.gingivalis, F.nucleatum, P.intermedia, T.denticola, D.streptococcus, E.faecalis, P.endodontics. Results: The number of bacteria in periodontal pocket was significantly reduced after root canal treatment (P<0.05). Among them, the difference of P.gingivalis, P.intermedia, and P.endodontics were the most obvious. Conclusion: The periodontal-derived combined periodontal and endodontic lesions are mainly caused by suspected pathogenic bacteria infection. Perfect root canal treatment can promote the prognosis of the combined periodontal and endodontic lesions caused by periodontal disease.

Key words: periodontal and endodontic lesions, root canal treatment, quantitative real-time PCR

Mireayikezi·MAMUTI, Jiangali·PAZILIBIEKE, , ZHAO Li, LU Hao, TIAN Shilin. Effect of Root Canal Therapy on Bacterial Colonization of Periodontal-derived Combined Periodontal and Endodontic Lesions[J]. Journal of Oral Science Research, 2021, 37(9): 830-834.

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