Effect of Puerarin and Naringin on the proliferation and Differentiation of Osteoblast.

Abstract

Abstract: Objective: To observe puerarin and naringin in the osteoblast of rats cultured in vitro. Methods: We used CCK-8 method to observe the effect of puerarin and naringin on the multiplicative function of the osteoblast of rats cultured in vitro and used ALP method to observe the effect of puerarin and naringin on the differentiated function of the osteblast of rats cultured in vitro. Results: The puerarin and naringin have obvious promptive effect on the multiplicative function of the osteoblast,but the effect on the multiplicative function of the osteoblast naringin value-added ability than puerarin.In terms of osteoblast differentiation,puerarin and naringin can improve the ALP activity of osteoblasts.But naringin is superior to the effects of puerarin on the influence on it. Conclusion: Puerarin and naringin have promoting effect on osteoblast proliferation and differentiation, but the effect of naringin on osteobast proliferation and differentiation is superior to the effect of puerarin.

Key words: Chinese medicine , Osteoblast proliferation and differentiation , Cell culture

CLC Number:

R781.4

ZHAO Gang, FU Yue-ming, LI De-chao, et al. Effect of Puerarin and Naringin on the proliferation and Differentiation of Osteoblast.[J]. Journal of Oral Science Research, 2015, 31(2): 130-132.

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