上颌窦侧壁开窗提升术中应用CGF的骨增量影像学评价与临床对照研究

doi:10.13701/j.cnki.kqyxyj.2021.02.016

口腔医学研究 ›› 2021, Vol. 37 ›› Issue (2): 162-166.DOI: 10.13701/j.cnki.kqyxyj.2021.02.016

上颌窦侧壁开窗提升术中应用CGF的骨增量影像学评价与临床对照研究

刘瑞敏^1,2, 鄢明东³, 黄文秀³, 吴东³, 陈江³

1. 福建省级机关医院(福建卫生职业技术学院附属医院)口腔中心福建福州 350003;
2.福建医科大学口腔医学院福建福州 350004;
3.福建医科大学附属口腔医院种植科福建福州 350004

收稿日期:2020-11-09 发布日期:2021-02-11
通讯作者: 陈江,E-mail:JiangChen@mail.fjmu.edu.cn
作者简介:刘瑞敏(1992~ ),女,山西太原人,医师,硕士,研究方向:口腔种植学。
基金资助:
福建省卫计委青年科研课题(编号:2017-2-34)

Imaging Evaluation and Clinical Controlled Study of Bone Augmentation with CGF in Lateral Maxillary Sinus Floor Augmentation

LIU Ruimin^1,2, YAN Mingdong³, HUANG Wenxiu³, WU Dong³, CHEN Jiang³

1. ORAL Center, Fujian Provincial Governmental Hospital(Affiliated Hospital of Fujian HeaLth College), Fuzhou 350003, China;
2. School of Stomatology,Fujian Medical University, Fuzhou 350004, China;
3. Department of Oral Implant, Stomatoloiacl Hospital Affiliated to Fujian Medical University, Fuzhou 350004, China

Received:2020-11-09 Published:2021-02-11

摘要/Abstract

摘要： 目的:探讨CGF在上颌窦底侧壁开窗提升术中的临床疗效和在Minics软件三维重建介导下的影像学变化。方法:收集因上颌后牙区骨量不足(<5 mm)拟行上颌窦侧壁开窗提升术的患者20例分为2组:实验组10例 (CGF联合骨替代材料组)和对照组10 例(仅使用骨替代材料组)。本研究为临床对照研究,通过Minics 19.0软件三维重建上颌窦内影像后,测量术后即刻及术后6个月窦内骨组织吸收率及骨密度值增长倍数的变化。评估术后并发症、术后满意度(VAS)、存留率等相关临床指标。结果:术后随访期内,所有种植体均取得了良好的临床疗效。影像学检评价:实验组平均骨吸收率显著大于对照组(P<0.05);实验组平均骨密度值显著高于对照组(P<0.05)。结论:上颌窦侧壁开窗提升术中CGF联合骨替代材料联合应用可以获得良好的短期疗效,且CGF的加入可以增加显著上颌窦内骨组织的密度,但其长期效果有待进一步随访观察。

关键词: 浓缩生长因子, 骨替代材料, 上颌窦底提升术, 影像学评价

Abstract: Objective: To explore the clinical efficacy of CGF combined with bone substitute material in maxillary sinus augmentation and the imaging changes by Mimics software. Methods: The patients were divided into two groups: experimental group (10 cases, CGF combined with bone substitute group) and control group (10 cases, only using bone substitute group). After introducing the CBCT data of the day and 6 months after lateral sinus lift into Mimics 19.0 software, the short-term bone resorption rate and the increased multiple of bone mineral density were calculated. Complications, postoperative satisfaction (VAS), and survival rate were evaluated. Results: During the follow-up period, all 20 patients achieved positive results. Imaging examination: the average bone resorption rate of the experimental group was significantly higher than that of the control group (P<0.05). The average bone mineral density of the experimental group was significantly higher than that of the control group (P<0.05). Conclusion: The combination of CGF and bone substitutes can achieve good clinical effect in the treatment of severe bone deficiency in the posterior maxillary region, and the addition of CGF can increase the density of bone tissue in maxillary sinus, but its long-term effect needs further follow-up.

Key words: concentrated growth factors, bone substitute materials, maxillary sinus augmentation, imaging evaluation

刘瑞敏, 鄢明东, 黄文秀, 吴东, 陈江. 上颌窦侧壁开窗提升术中应用CGF的骨增量影像学评价与临床对照研究[J]. 口腔医学研究, 2021, 37(2): 162-166.

LIU Ruimin, YAN Mingdong, HUANG Wenxiu, WU Dong, CHEN Jiang. Imaging Evaluation and Clinical Controlled Study of Bone Augmentation with CGF in Lateral Maxillary Sinus Floor Augmentation[J]. Journal of Oral Science Research, 2021, 37(2): 162-166.

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上颌窦侧壁开窗提升术中应用CGF的骨增量影像学评价与临床对照研究

Imaging Evaluation and Clinical Controlled Study of Bone Augmentation with CGF in Lateral Maxillary Sinus Floor Augmentation

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