口腔医学研究 ›› 2026, Vol. 42 ›› Issue (6): 524-528.DOI: 10.13701/j.cnki.kqyxyj.2026.06.011

• 口腔颌面外科学研究 • 上一篇    下一篇

颌骨腺样囊性癌临床及CT影像学特征的回顾性研究

冯英连1, 帕克扎提·色依提1, 夏舒2, 王铁梅1*   

  1. 1.南京大学医学院附属口腔医院,南京市口腔医院口腔颌面医学影像科,南京大学口腔医学研究所 江苏 南京 210008;
    2.南京大学医学院附属口腔医院,南京市口腔医院口腔病理科,南京大学口腔医学研究所 江苏 南京 210008
  • 收稿日期:2025-06-11 出版日期:2026-06-28 发布日期:2026-06-23
  • 通讯作者: *王铁梅,E-mail:tiemei106@263.net
  • 作者简介:冯英连(1989~),女,南京人,硕士,主治医师,研究方向:成釉细胞瘤的影像学诊断、功能性MR成像。

Clinical and CT Imaging Features of Intraosseous Adenoid Cystic Carcinoma of the Jaw: A Retrospective Study

FENG Yinglian1, Pakezhati·SEYITI1, XIA Shu2, WANG Tiemei1*   

  1. 1. Department of Oral and Maxillofacial Medical Imaging, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing 210008, China;
    2. Department of Oral Pathology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing 210008, China
  • Received:2025-06-11 Online:2026-06-28 Published:2026-06-23

摘要: 目的:探讨发生在颌骨的腺样囊性癌(intraosseous adenoid cystic carcinoma,IACC)的CT影像学特征,并分析其与临床相关性。方法:收集2015年1月至2025年4月符合纳入标准的IACC患者,并回顾性分析其影像学及临床特征。结果:本次研究共纳入10例IACC患者,中位发病年龄为48岁,男女比例为6∶4,好发部位为上颌骨后部(50%,5/10),60%(6/10)患者早期有神经症状表现。影像学分型为肿块型(50%,5/10)及类囊型(50%,5/10),肿块型IACC表现为实性软组织肿块伴颌骨骨质破坏,边缘不规整;类囊型IACC可见囊实性软组织肿块伴膨胀性骨质吸收菲薄,边缘较规整,其中80%(4/5)病例病灶内可见点片状或纤维索条状高密度影,有助于与其他颌骨病变相鉴别。结论:颌骨腺样囊性癌较为罕见,易与颌骨其他肿瘤混淆,总结其临床及影像学特征有助于辅助临床诊断及引导治疗。

关键词: 颌骨, 腺样囊性癌, 影像学特征, 临床表现

Abstract: Objective: To investigate the CT imaging features of intraosseous adenoid cystic carcinoma (intraosseous adenoid cystic carcinoma, IACC) occurring in the jaw and analyze their clinical correlation. Methods: Patients with IACC who met the inclusion criteria between January 2015 and April 2025 were enrolled. A retrospective analysis was conducted on their clinical and CT imaging features. Results: A total of 10 IACC patients were included in this study, with a mean age of 48 years and a male-to-female ratio of 6∶4. The most common site was the posterior maxilla (50%, 5/10), and 60% (6/10) exhibited early neurological symptoms. The imaging findings were classified into mass-type (50%, 5/10) and cyst-like type (50%, 5/10). Mass-type IACC presented as solid soft tissue masses with irregular bone destruction, while cyst-like IACC showed cystic-solid soft tissue masses accompanied by expansile bone thinning and relatively smooth margins. Notably, 80% (4/5) of the cyst-like cases exhibited punctate or fibrous striated high-density shadows within the lesions, which may aid in differentiating them from other locally aggressive odontogenic cystic lesions of the jaw. Conclusion: Intraosseous adenoid cystic carcinoma is rare and easily confused with other jaw tumors. A summary of its clinical and radiological characteristics may improve diagnostic and therapeutic decisions.

Key words: jaw, adenoid cystic carcinoma, imaging characteristics, clinical manifestations