口腔医学研究

口腔医学研究 ›› 2017, Vol. 33 ›› Issue (7): 762-765.DOI: 10.13701/j.cnki.kqyxyj.2017.07.018

• 临床研究论著 • 上一篇    下一篇

维药买朱尼对种植体周围炎龈沟液中白细胞介素-1β和牙周指数的影响

古丽再努·依不拉音, 吐逊阿依·阿迪力, 任家卉, 杨超, 尼加提·吐尔逊*   

  1. 新疆医科大学第二附属医院 新疆 乌鲁木齐 830063
  • 收稿日期:2016-12-20 出版日期:2017-07-20 发布日期:2017-07-27
  • 通讯作者: 尼加提·吐尔逊,E-mail:kqnijate@126.com
  • 作者简介:古丽再努·依不拉音(1990~ ),女,维吾尔族人,新疆哈密市人,硕士在读,主要从事口腔种植学研究。
  • 基金资助:
    中华口腔医学会西部行口腔医学临床科研基金项目(编号:CSA-W2015-05)

Effect of Uygur Medicine Maizhuni on IL-1β in Crevicular Fluid and Periodontal Index in Peri-implantitis.

Gulizainv·Yibulayin, Tuxunayin·Adili,REN Jia-hui,YANG Chao,Nijiati·Tuerxun*   

  1. The Second Affiliated Hospital of XinJiang Medical University, Urumqi 830063, China
  • Received:2016-12-20 Online:2017-07-20 Published:2017-07-27

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摘要： 目的:通过买朱尼对IL-1β有抑制作用机制尝试探讨维药买朱尼对种植体周围炎相关因子IL-1β和牙周指数的影响。方法:接受种植义齿修复的100名18～55岁患者分为标准对照组和实验组各50例,标准对照组术前口服阿莫西林;实验组术前口服阿莫西林,术后7 d拆线2组均测IL-1β、菌斑指数、出血指数。实验组口服4个疗程维药买朱尼。1个月后复诊测量IL-1β、菌斑指数、出血指数。应用SPSS 22.0进行数据统计分析。结果:对照组4周后IL-1β水平与1周后IL-1β水平相比显著下降(P<0.05),4周后出血指数与1周后出血指数相比显著下降(P<0.05),4周后菌斑指数与1周后菌板指数差异不显著;实验组4周后IL-1β水平与1周后IL-1β水平相比显著下降(P<0.05),4周后出血指数与1周后出血指数相比显著下降(P<0.05),4周后菌斑指数与1周后菌斑指数差异不显著。4周后,实验组IL-1β水平和出血指数显著低于对照组,菌斑指数无显著差异。结论:维药买朱尼对种植体周围龈沟液中IL-1β有抑制作用,对种植体周围炎症有很好的临床疗效。

关键词: 种植体周围炎, 白细胞介素-1β, 维药买朱尼, 龈沟液, 牙周指数

Abstract: Objective: To explore the effect of Uygur medicine Maizhuni on IL-1β in crevicular fluid and periodontal index in peri-implantitis. Methods: One hundred patients at the age of 18-55 years were divided into two groups (control group and experimental group). Patients in both groups received oral amoxicillin before surgery. Seven days after suture removal. IL-1β, plaque index, and bleeding index were measured. Patients in the experimental group received four courses of maizhuni treatment. One month later, IL-1β, plaque index and bleeding index were re-measured. Results: IL-1β was significantly reduced in the experimental group (P<0.05). However, there was no significant difference in the plaque index. Conclusion: Maizhuni may be used to treat peri-implantitis.

Key words: Peri-implantitis, Interleukin-1β , Maizhuni , Gingival crevicular fluid, Periodontal index

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