冰模板技术及其在口腔医学领域的应用进展

doi:10.13701/j.cnki.kqyxyj.2023.09.001

口腔医学研究 ›› 2023, Vol. 39 ›› Issue (9): 767-770.DOI: 10.13701/j.cnki.kqyxyj.2023.09.001

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冰模板技术及其在口腔医学领域的应用进展

周延民^1,2*, 杨亿鑫^1,2

1.吉林大学口腔医院口腔种植中心吉林长春 130021;
2.吉林省牙发育及颌骨重塑与再生重点实验室吉林长春 130021

收稿日期:2023-03-15 出版日期:2023-09-28 发布日期:2023-09-25
通讯作者: *周延民,E-mail:zhouym@jlu.edu.cn
基金资助:
吉林省自然科学基金(编号:20200201302JC)

Ice-templating Technique and Its Application in Stomatology

ZHOU Yanmin^1,2*, YANG Yixin^1,2

1. Department of Implantology, Hospital of Stomatology, Jilin University, Changchun 130021, China;
2. Jilin Provincial Engineering Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, China

Received:2023-03-15 Online:2023-09-28 Published:2023-09-25

摘要/Abstract

摘要： 冰模板技术是利用冰晶体的定向生长,通过调节冷冻过程中的温度分布、降温速率以及降温方向等参数从而控制材料宏观和微观形貌,进而制备大尺度有序多孔材料的技术。近年来在生物医学领域,特别是组织工程仿生支架材料合成方面展现出独特的优势。在口腔医学中,冰模板技术当前主要用于牙周组织和牙体组织仿生修复支架材料的制备,以及口腔临床修复材料合成和口腔来源种子细胞培养等方面。本文就冰模板技术的原理、技术要点以及在口腔医学领域的应用现状进行综述,并对其未来的应用前景进行展望。

关键词: 冰模板, 口腔医学, 组织工程, 支架材料

Abstract: Ice-templating technique is a technology that uses the directional growth of ice crystals to control the macroscopic and microscopic morphology of materials by adjusting the temperature distribution, cooling rate, and cooling direction in the freezing process, and then to prepare large-scale ordered porous materials. In recent years, it has shown unique advantages in the field of biomedicine, especially in the synthesis of tissue engineering biomimetic scaffolds. In stomatology, the current ice-templating technique is mainly used in the preparation of periodontal and dental tissue biomimetic repair scaffolds, as well as the synthesis of repairing materials and the culture of seeded cells from oral tissue. This paper summarizes the principle, technical points, and application status of ice-templating technique in stomatology, and looks forward to its application prospect in the future.

Key words: ice-templating technique, stomatology, tissue engineering, scaffold material

周延民, 杨亿鑫. 冰模板技术及其在口腔医学领域的应用进展[J]. 口腔医学研究, 2023, 39(9): 767-770.

ZHOU Yanmin, YANG Yixin. Ice-templating Technique and Its Application in Stomatology[J]. Journal of Oral Science Research, 2023, 39(9): 767-770.

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冰模板技术及其在口腔医学领域的应用进展

Ice-templating Technique and Its Application in Stomatology

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