口腔医学研究 ›› 2016, Vol. 32 ›› Issue (11): 1213-1216.DOI: 10.13701/j.cnki.kqyxyj.2016.11.026

• 综述 • 上一篇    下一篇

口腔扁平苔藓的目标治疗:观点和展望

卢锐   

  1. 湖北省口腔基础医学重点实验室-省部共建国家重点实验室培育基地暨口腔生物医学教育部重点实验室(武汉大学);武汉大学口腔医院口腔黏膜科 湖北 武汉 430079
  • 收稿日期:2016-02-19 出版日期:2016-11-25 发布日期:2016-11-25
  • 作者简介:卢锐(1982~ ),男,湖南长沙人,博士,副主任医师,主要从事口腔黏膜病的临床、科研及教学工作,电话:027-87686213。
  • 基金资助:
    国家自然科学基金资助项目(编号:81200797)

Treat-to-target in Oral Lichen Planus: Perspective and Prospective

LU Rui   

  1. The State Key Laboratory Breeding Base of Basic Science of Stomatology, Hubei province and Key Laboratory of Oral Biomedicine (Wuhan University) Ministry of Education; Department of Oral Medicine, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2016-02-19 Online:2016-11-25 Published:2016-11-25

摘要: 口腔扁平苔藓(OLP)目前仍属无法治愈的慢性疾病,如何控制其病情反复加重、维持长期的缓解状态仍是临床上难以解决的问题。目标治疗是一种新的慢性病治疗理念,强调疾病治疗应通过定期病情评估和调整治疗方案,以达到病情缓解为主要目标。近年来,目标治疗策略已广泛应用于多个医学领域,并显著改善了患者的病情和预后。本文将联系目标治疗的基本理念和OLP的疾病特点,首次对OLP目标治疗的可行性和关键问题进行展望和讨论,以期为OLP治疗模式的发展提供参考。

关键词: 口腔扁平苔藓, 治疗, 目标治疗, 展望

Abstract: Hitherto, oral lichen planus (OLP) is still an uncurable chronic disease. How to control the disease relapse and maintain long-term remission have not been well resolved. Treat-to-target is a novel treatment concept for the chronic diseases, which highlights treatment toward a therapeutic target of clinical remission by regular assessing disease activity and adjusting therapy accordingly. In recent years, this strategy has been widely applied in many areas of medicine and markedly improves the patients' condition and outcome. According to the concept of treat-to-target and current situation of OLP treatment, this article proposes an treat-to-target strategy in OLP and discusses its feasibility and key issues, aiming to provide an advisory opinion for the improvement of OLP treatment mode.

Key words: Oral lichen planus, Treatment, Treat-to-target, Prospective

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