Pathologic Changes of Synovial Chondromatosis of Temporomandibular Joint.

doi:10.13701/j.cnki.kqyxyj.2017.11.001

Abstract

Abstract: Objective: To investigate the histological features of synovial chondromatosis (SC) of temporomandibular joint (TMJ) and the key to promote pathogenic process. Methods: Loose bodies(LBs)and synovium specimens were treated with histological methods. Results: During Milgram phaseⅠ, cartilaginous nodules (CNs) with a length of 30μm formed in synovium's sublining layer rich in blood vessels. During Milgram phaseⅡ, CNs with a length of about 0.5mm detached from synovium and became LBs which were nurtured by synovial fluid. The length of LB could increase to 3 mm. During Milgram phase Ⅲ, bone trabecular replaced the majority of cartilaginous extracellular matrix in the LB with a length of 4.3mm. Conclusion: During Milgram phaseⅠ, angiogenesis guaranteed enough nutrients supply for CNs formation. During Milgram phaseⅡ, enough nutrients supply from synovial fluid facilitated further volume increase of LBs. During Milgram phase Ⅲ, LB suffered from ossification and structure changes in order for more nutrients permeation into deep area. Therefore, the need of CNs or LBs for nutrients promoted the pathogenic process of TMJSC.

Key words: Synovial chondromatosis, Milgram classification, Synovium cartilaginous metaplasia, Ossification

CLC Number:

R782.6

LI Ying-jie, FENG Ya-ping, DENG Mo-hong, LONG Xing. Pathologic Changes of Synovial Chondromatosis of Temporomandibular Joint.[J]. Journal of Oral Science Research, 2017, 33(11): 1135-1138.

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