Abstract: Objective: To investigate the imaging features of keratoameloblastoma (KA) and discuss its differential diagnosis after reviewing the literatures.Methods: Three patients who were diagnosed pathologically as KA were involved in this study from 2011 to 2017 in the Department of Oral and Maxillofacial Radiology.The radiological appearances were retrospected and summarized.After reviewing the literatures, its differential diagnosis was discussed.Results: Among 3 cases, the lesions were all located in the left side of mandibular body and ascending branch.The common radiological findings were expansible inhomogeneous lesions with septa, as well as scalloping and worm-eat borders.Heterogeneous high attenuation foci intermixed with areas were found, part of which had scarred calcification.The differential diagnosis included primary intraosseous carcinomas, malignant ameloblastoma, and central giant cell lesion.Conclusion: Both benign and malignant radiological characteristics can be seen on the imaging of KA.The identification of typical radiographic features is helpful to diagnose the KA and make surgical decision.More case reports are important to precisely diagnose this extremely rare histological ameloblastoma.

Key words: Keratoameloblastoma, Radiographic features, Differential diagnosis