Journal of Oral Science Research ›› 2019, Vol. 35 ›› Issue (6): 511-516.DOI: 10.13701/j.cnki.kqyxyj.2019.06.001

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Advances in Nanomedicine Strategies to Target Tumor-associated Macrophage

SUN Hong-chen, LI Xing   

  1. School of Stomatology, China Medical University, Shenyang 110000, China.
  • Received:2019-04-30 Online:2019-06-28 Published:2019-06-27

Abstract: Tumor associated macrophage (TAM), one of the most important immune cells in tumor microenvironment, plays an important part in the occurrence and development of tumor. TAM-targeted immunotherapy is the frontier and hotspot of tumor therapy. Due to its excellent physical and chemical properties, nano-drug delivery system provides a new idea and direction for targeted regulation of TAM. In this paper, the current situation of targeted regulation of TAM by nanomaterials to kill tumor cells is reviewed.

Key words: Tumor associated macrophage, Target therapy, Nanomaterials