Journal of Oral Science Research ›› 2020, Vol. 36 ›› Issue (8): 719-722.DOI: 10.13701/j.cnki.kqyxyj.2020.08.004

Previous Articles     Next Articles

Research Progress of Parathyroid Hormone in Oral Therapy

ZHANG Yaoyuan, WANG Lin*   

  1. Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University; Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing 210029, China
  • Received:2019-08-16 Online:2020-08-28 Published:2020-08-18

Abstract: Parathyroid hormone (PTH) is an important regulator of calcium and phosphorus homeostasis. It has dual regulatory effects on bone metabolism, which can promote bone formation and can accelerate bone absorption. The dual effects of PTH on bone metabolism mainly depend on its dosage, mode of administration, and physical body's PTH level. Intermittent low-dose PTH plays an active role in the treatment of oral diseases. In the essay, the regulation mechanism of PTH on craniomaxillofacial bone and the analysis of PTH application in oral therapy are comprehensively summarized, which provides theory foundation and reference for PTH application on oral therapy.

Key words: parathyroid hormone, craniomaxillofacial bone metabolism, oral therapy, application