Effects of Different Skin Flaps on Recovery and SA and sIL-2R Levels in Patients with Oral and Maxillofacial Soft Tissue Defects

doi:10.13701/j.cnki.kqyxyj.2021.05.019

Abstract

Abstract: Objective: To explore the effects of different skin flaps on the recovery and sialic acid (SA) and soluble interleukin-2 receptor (sIL-2R) levels in patients with oral and maxillofacial soft tissue defects. Methods: Sixty-six patients with oral and maxillofacial soft tissue defects treated in Qinghai Provincial People's Hospital from January 2015 to January 2017 were selected as the research subjects. They were randomly divided into three groups (A, B, and C) with 22 cases in each group. Group A was treated with traditional anterolateral femoral flap, group B was treated with lateral femoral cutaneous nerve free anterolateral femoral flap, and group C was treated with forearm flap. The functional recovery of patients after 6 months of follow-up was compared, and patient satisfaction, serum SA, sIL-2R expression levels, and the incidence of oral adverse conditions in each group of patients were recorded and compared. Results: After 6 months of follow-up, the survival rate of flap was 96.97%. The scores of shape repair, mouth opening, closure, eating, language function, swallowing function, chewing function, and occlusal function of group B were significantly better than those of group A and group C (P<0.001 or P<0.05). And the postoperative sensory excellent rate and satisfaction of group B were higher than those of group A and group C (P<0.05). One month after surgery, the decrease in group B was better than those in groups A and C. The decrease in group A was better than that in group C (P<0.05). Compared with patients in group C, the incidence of complications in group B was reduced (P<0.05). Compared with patients in group A, the incidence of paresthesia and unresponsiveness in group B was reduced (P<0.05). Conclusion: The free anterolateral femoral skin flap is the best treatment for skin repair and reconstruction of oral and maxillofacial soft tissue defects, which is conducive to reduce the risk of donor site complications and improve the patient's functional recovery

Key words: oral and maxillofacial soft tissue defect, anterolateral femoral skin flap, lateral femoral cutaneous nerve, sialic acid, forearm flap repair, soluble interleukin-2 receptor

HAN Xiaodong, CHEN Donghui, ZHAO Furong. Effects of Different Skin Flaps on Recovery and SA and sIL-2R Levels in Patients with Oral and Maxillofacial Soft Tissue Defects[J]. Journal of Oral Science Research, 2021, 37(5): 474-478.

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