Journal of Oral Science Research ›› 2022, Vol. 38 ›› Issue (10): 907-912.DOI: 10.13701/j.cnki.kqyxyj.2022.10.001

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Biological Insights into Orthodontically Induced Root Resorption

HE Hong*, DU Mingyuan   

  1. Department of Orthodontics, School and Hospital of Stomatology, The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2022-07-15 Online:2022-10-28 Published:2022-10-20

Abstract: Orthodontically induced root resorption is a common complication caused by orthodontic force, which is mainly characterized by the destruction of cementum and other dental tissues. It is mainly caused by local aseptic inflammation induced by orthodontic force and regulated by multiple cells and related molecules. Orthodontically induced root resorption is highly concerned by orthodontists due to its high incidence and potential impact on the health of periodontal tissues. In this article, biological characteristics of the progress of orthodontically induced root resorption, the main involved cells, related regulatory molecules, and cementum repair are described.

Key words: orthodontically induced root resorption, cementum, aseptic inflammation