Retrospective Study of the Effect of Different Gingival Phenotypes on Clinical Efficacy of Periodontal Tissue Regeneration Surgery

doi:10.13701/j.cnki.kqyxyj.2024.02.004

Abstract

Abstract: Objective: To evaluate the effect of gingival phenotype on clinical efficacy after periodontal tissue regeneration surgery by analyzing relevant clinical indexes. Methods: Thirty patients who need periodontal tissue regeneration surgery were selected, with a total of 40 affected teeth, including 20 thin gingival type and 20 thick gingival type each. The probing depth (PD), gingival recession depth (GRD), clinical attachment loss (CAL), and keratinized tissue width (KTW) of the affected teeth were recorded and compared before and 6 months after surgery. Results: In the thick gingival type group, there were statistically significant differences in the PD, CAL, and KTW at 6 months after surgery in contrast to before surgery (P<0.05). In the thin gingival type group, there were statistically significant differences in the PD, GRD, and CAL at 6 months after surgery in contrast to before surgery (P<0.05). There was statistically significant difference in the changes of ΔCAL, ΔGRD, and ΔKTW before and 6 months after surgery between thin gingival type and thick gingival type groups (P<0.05). Correlation analysis showed that gingiva thickness (GT) was negatively correlated with ΔGRD, and positively correlated with ΔKTW and ΔCAL. Conclusion: Gingival phenotype is an important factor affecting the clinical efficacy of periodontal tissue regeneration surgery. The improvement of CAL, the increase of KTW, and the prognosis of GRD in patients with thick gingival type were better than those with thin gingival type.

Key words: gingival phenotype, periodontal regenerative surgery, keratinized tissue width, gingival recession

FU Junbo, DA Haiqin, ZHOU Zhanhao, TAO Shanyue, CHEN Ying. Retrospective Study of the Effect of Different Gingival Phenotypes on Clinical Efficacy of Periodontal Tissue Regeneration Surgery[J]. Journal of Oral Science Research, 2024, 40(2): 113-117.

References

[1] Fine DH, Patil AG, Loos BG. Classification and diagnosis of aggressive periodontitis [J]. J Periodontol, 2018, 89 Suppl 1:S103-S119.
[2] Sallum EA, Ribeiro FV, Ruiz KS, et al. Experimental and clinical studies on regenerative periodontal therapy [J]. Periodontol 2000, 2019, 79(1):22-55.
[3] 石宇彤,王翠,胡文杰,等.运用牙周再生性手术及翻瓣骨成形术治疗牙周炎的临床效果观察(附1例报告)[J].中国实用口腔科杂志,2020,13(3):130-138.
[4] Cheng J, Cheng L, Kong L, et al. Clinical observation of porcine collagen membrane + artificial bovine bone granules guided tissue regeneration combined with autologous CGF in the treatment of severe periodontitis bone defect [J]. Pak J Med Sci, 2023, 39(3):710-714.
[5] Anderegg CR, Metzler DG, Nicoll BK. Gingiva thickness in guided tissue regeneration and associated recession at facial furcation defects [J]. J Periodontol, 1995, 66(5):397-402.
[6] Jepsen S, Caton JG, Albandar JM, et al. Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions [J]. J Periodontol, 2018, 89 Suppl 1:S237-S248.
[7] Malpartida Carrillo V, Tinedo Lopez PL, Guerrero ME, et al. Periodontal phenotype: A review of historical and current classifications evaluating different methods and characteristics [J]. J Esthet Restor Dent, 2021, 33(3):432-445.
[8] Kim DM, Bassir SH, Nguyen TT. Effect of gingival phenotype on the maintenance of periodontal health: An American Academy of Periodontology best evidence review [J]. J Periodontol, 2020, 91(3):311-338.
[9] Huang LH, Neiva RE, Soehren SE, et al. The effect of platelet-rich plasma on the coronally advanced flap root coverage procedure: a pilot human trial [J]. J Periodontol, 2005, 76(10):1768-1777.
[10] Kan JY, Morimoto T, Rungcharassaeng K. Gingival biotype assessment in the esthetic zone: visual versus direct measurement [J]. Int J Periodontics Restorative Dent, 2010, 30(3):237-243.
[11] Shaikh MS, Pisani F, De Vito D, et al. Long-term clinical performance of regeneration versus conservative surgery in the treatment of infra-bony defects:A systematic review [J]. J Int Acad Periodontol, 2021, 23(1):31-56.
[12] Batista EJ, Novaes AJ, Simonpietri JJ, et al. Use of bovine-derived anorganic bone associated with guided tissue regeneration in intrabony defects. Six-month evaluation at re-entry [J]. J Periodontol, 1999, 70(9):1000-1007.
[13] Cortellini P, Tonetti MS. Clinical concepts for regenerative therapy in intrabony defects [J]. Periodontology 2000, 2015, 68(1):282-307.
[14] Tonetti MS, Prato GP, Cortellini P. Factors affecting the healing response of intrabony defects following guided tissue regeneration and access flap surgery [J]. J Clin Periodontol, 1996, 23(6):548-556.
[15] Górski B, Kaczyski T, Miskiewicz A, et al. Early postoperative healing following guided tissue regeneration in aggressive periodontitis patients [J]. Dent Med Probl, 2018, 55(3):289-297.
[16] 杨大国,任秀云.牙龈表型分型的现状与展望[J].口腔医学研究,2022,38(1):20-23.
[17] 陈子圆,钟金晟,欧阳翔英,等.牙龈退缩患牙的牙龈厚度评估[J].北京大学学报(医学版),2020,52(2):339-345.
[18] Kim Y, Park J, Jang Y, et al. Accuracy of periodontal probe visibility in the assessment of gingival thickness [J]. J Periodontal Implant Sci, 2021, 51(1):30-39.
[19] 张薇,赵万民,郑亚飞,等.牙周表型的分类、测量及临床意义[J].实用口腔医学杂志,2021,37(3):414-418.
[20] Hwang D, Wang H. Flap thickness as a predictor of root coverage: A systematic review [J]. J Periodontol, 2006, 77(10):1625-1634.
[21] Levine RA, Saleh MHA, Dias DR, et al. Periodontal regeneration risk assessment in the treatment of intrabony defects [J]. Clin Adv Periodontics, 2023.
[22] Fischer KR, Künzlberger A, Donos N, et al. Gingival biotype revisited-novel classification and assessment tool [J]. Clin Oral Investig, 2018, 22(1):443-448.
[23] Gonçalves Motta SH, Ferreira Camacho MP, Quintela DC, et al. Relationship between clinical and histologic periodontal biotypes in humans [J]. Int J Periodontics Restorative Dent, 2017, 37(5):737-741.
[24] Le NM, Song S, Zhou H, et al. A noninvasive imaging and measurement using optical coherence tomography angiography for the assessment of gingiva: An in vivo study [J]. J Biophotonics, 2018, 11(12):e201800242.
[25] Vlachodimou E, Fragkioudakis I, Vouros I. Is there an association between the gingival phenotype and the width of keratinized gingiva? A systematic review [J]. Dent J (Basel), 2021, 9(3):34.