Exploring Composition and Succession of Peri-implant Microbiota Based on Metagenomics

doi:10.13701/j.cnki.kqyxyj.2025.10.008

Abstract

Abstract: Objective: To explore the composition and successional process of the microbial community surrounding dental implants. Methods: Samples of peri-implant and adjacent gingival crevicular fluid were collected from 19 patients at different stages after dental prosthesis placement (30 minutes, 1 week, 2 weeks, 3 weeks, and 4 weeks). The composition of the microbial community was analyzed using metagenomic sequencing technology. Results: The species diversity and abundance of dental implants were lower compared to natural teeth. There were 4, 8, and 18 species with differences between natural teeth and dental implants at the phylum, genus, and species levels, respectively. The genera Actinomyces and Capnocytophaga were the major contributors to these differences. At the genus level, Streptococcus was the most abundant genus in all four groups of dental implants; at the species level, the abundance change patterns of the top 200 species across different time points were complex. Conclusion: A relatively complex microbial community had formed around the implants one week after prosthesis placement, with Streptococcus being the pioneer species.

Key words: dental implant, oral microbiota, metagenomics

LIU Yibing, XIANG Yufei, LI Jiayin, GUO Jiating, LIANG Wei, LI Mengting, ZHOU Shuo, CUI Xiaoxuan, ZHOU Qin. Exploring Composition and Succession of Peri-implant Microbiota Based on Metagenomics[J]. Journal of Oral Science Research, 2025, 41(10): 883-889.

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