Research Progress on Treatment of White Spot Lesions During Fixed Orthodontic Treatment

doi:10.13701/j.cnki.kqyxyj.2021.06.002

Abstract

Abstract: White spot lesion is a common complication after orthodontic treatment. These lesions tend to appear rough and chalky on the smooth surfaces, and hence affect the aesthetic and function of teeth. Various interventions have been employed in managing white spot lesion after orthodontic treatment. The purpose of this article is to review the latest research and therapeutic effects of these treatments, and to provide new ideas and new basis for clinical practice and fundamental research.

Key words: fixed orthodontic treatment, white spot lesions, enamel demineralization, remineralization

WU Wenzhi, XIE Zhijian. Research Progress on Treatment of White Spot Lesions During Fixed Orthodontic Treatment[J]. Journal of Oral Science Research, 2021, 37(6): 489-492.

References

[1] Sundararaj D, Venkatachalapathy S, Tandon A, et al. Critical evaluation of incidence and prevalence of white spot lesions during fixed orthodontic appliance treatment: A meta-analysis [J]. J Int Soc Prev Community Dent, 2015, 5(6): 433-439.
[2] Shungin D, Olsson AI, Persson M. Orthodontic treatment-related white spot lesions: a 14-year prospective quantitative follow-up, including bonding material assessment [J]. Am J Orthod Dentofacial Orthop, 2010, 138(2): 136.e1-136.e8.
[3] Meligy O, Ibrahim S, Alamoudi N. Resin infiltration of non-cavitated proximal caries lesions: a literature review [J]. J Oral Hyg Health, 2018, 6(1): 235-243.
[4] 宋玉梦,郭威.渗透树脂治疗早期龋的研究新进展[J].口腔医学, 2016, 36(9): 857-860.
[5] Araujo G, Naufel F, Alonso R, et al. Influence of staining solution and bleaching on color stability of resin used for caries infiltration [J]. Oper Dent, 2015, 40(6): E250-E256.
[6] Yetkiner E, Wegehaupt F, Wiegand A, et al. Colour improvement and stability of white spot lesions following infiltration, micro-abrasion, or fluoride treatments in vitro [J]. Eur J Orthod, 2014, 36(5): 595-602.
[7] Knosel M, Eckstein A, Helms HJ. Long-term follow-up of camouflage effects following resin infiltration of post orthodontic white-spot lesions in vivo [J]. Angle Orthod, 2019, 89(1): 33-39.
[8] Murphy TC, Willmot DR, Rodd HD. Management of postorthodontic demineralized white lesions with microabrasion: a quantitative assessment [J]. Am J Orthod Dentofacial Orthop, 2007, 131(1): 27-33.
[9] Gu X, Yang L, Yang D, et al. Esthetic improvements of postorthodontic white-spot lesions treated with resin infiltration and microabrasion: A split-mouth, randomized clinical trial [J]. Angle Orthod, 2019, 89(3): 372-377.
[10] Ntovas P, Rahiotis C. A clinical guideline for caries infiltration of proximal enamel lesions with resins [J]. Br Dent J, 2018, 225(4): 299-304.
[11] ten Cate JM. Contemporary perspective on the use of fluoride products in caries prevention [J]. Br Dent J, 2013, 214(4): 161-167.
[12] Fernandez-Ferrer L, Vicente-Ruiz M, Garcia-Sanz V, et al. Enamel remineralization therapies for treating postorthodontic white-spot lesions: A systematic review [J]. J Am Dent Assoc, 2018, 149(9): 778-786.e2.
[13] Urquhart O, Tampi MP, Pilcher L, et al. Nonrestorative treatments for caries: systematic review and network meta-analysis [J]. J Dent Res, 2019, 98(1): 14-26.
[14] Kannan A, Padmanabhan S. Comparative evaluation of Icon resin infiltration and Clinpro XT varnish on colour and fluorescence changes of white spot lesions: a randomized controlled trial [J]. Prog Orthod, 2019, 20(1): 23.
[15] Lopatiene K, Borisovaite M, Lapenaite E. Prevention and treatment of white Spot lesions during and after treatment with fixed orthodontic appliances: a systematic literature review [J]. J Oral Maxillofac Res, 2016, 7(2): e1.
[16] Willmot D. White lesions after orthodontic treatment: does low fluoride make a difference? [J]. J Orthod, 2004, 31(3): 235-242.
[17] Bock NC, Seibold L, Heumann C, et al. Changes in white spot lesions following post-orthodontic weekly application of 1.25 per cent fluoride gel over 6 months-a randomized placebo-controlled clinical trial. Part Ⅱ: clinical data evaluation [J]. Eur J Orthod, 2017, 39(2): 144-152.
[18] Reynolds EC. Calcium phosphate-based remineralization systems: scientific evidence? [J]. Aust Dent J, 2008, 53(3): 268-273.
[19] Bailey D, Adams G, Tsao C, et al. Regression of post-orthodontic lesions by a remineralizing cream [J]. J Dent Res, 2009, 88(12): 1148-1153.
[20] Mendes AC, Restrepo M, Bussaneli D, et al. Use of casein amorphous calcium phosphate (CPP-ACP) on white-spot lesions: randomised clinical trial [J]. Oral Health Prev Dent, 2018, 16(1): 27-31.
[21] Karabekiroglu S, Unlu N, Kucukyilmaz E, et al. Treatment of post-orthodontic white spot lesions with CPP-ACP paste: A three year follow up study [J]. Dent Mater J, 2017, 36(6): 791-797.
[22] Yeoh ES, Le T, Maravilla J, et al. Clinical evidence in the treatment of white spot lesions following fixed orthodontic therapy: A meta-analysis [J]. Aust Orthod J, 2018, 34(1): 45-59.
[23] Pithon MM, Baião FS, Sant'Anna LID, et al. Effectiveness of casein phosphopeptide-amorphous calcium phosphate-containing products in the prevention and treatment of white spot lesions in orthodontic patients: A systematic review [J]. J Investig Clin Dent, 2019, 10(2): e12391.
[24] Alkilzy M, Santamaria RM, Schmoeckel J, et al. Treatment of carious lesions using self-assembling peptides [J]. Adv Dent Res, 2018, 29(1): 42-47.
[25] Brunton P, Davies R, Burke J, et al. Treatment of early caries lesions using biomimetic self-assembling peptides-a clinical safety trial [J]. Br Dent J, 2013, 215(4): E6.
[26] Kirkham J, Firth A, Vernals D, et al. Self-assembling peptide scaffolds promote enamel remineralization [J]. J Dent Res, 2007, 86(5): 426-430.
[27] Brunton PA, Davies RP, Burke JL, et al. Treatment of early caries lesions using biomimetic self-assembling peptides--a clinical safety trial [J]. Br Dent J, 2013, 215(4): e6.
[28] Schmidlin P, Zobrist K, Attin T, et al. In vitro re-hardening of artificial enamel caries lesions using enamel matrix proteins or self-assembling peptides [J]. J Appl Oral Sci, 2016, 24(1): 31-36.
[29] Takahashi F, Kurokawa H, Shibasaki S, et al. Ultrasonic assessment of the effects of self-assembling peptide scaffolds on preventing enamel demineralization [J]. Acta Odontol Scand, 2016, 74(2): 142-147.
[30] Schlee M, Schad T, Koch JH, et al. Clinical performance of self-assembling peptide P11-4 in the treatment of initial proximal carious lesions: A practice-based case series [J]. J Investig Clin Dent, 2018, 9(1):e12286.
[31] Gozetici B, Ozturk-Bozkurt F, Toz-Akalin T. Comparative evaluation of resin infiltration and remineralisation of noncavitated smooth surface caries lesions: 6-month results [J]. Oral Health Prev Dent, 2019, 17(2): 99-106.