Regulation of Phosvitin on Remineralization of Demineralized Dentin by Bioactive Glass

doi:10.13701/j.cnki.kqyxyj.2021.02.007

Abstract

Abstract: Objective: To investigate the regulation of phosvitin (PV) on remineralization of demineralized dentin by bioactive glass (BG). Methods: 120 dentin slices were prepared and randomly divided into 6 groups: Group A was treated with SBF as the control group, Group B was treated with 100 mg/L PV, Group C was treated with 500 mg/L PV, Group D was treated with SBF and BG, Group E was treated with 100 mg/L PV and BG, and Group F was treated with 500 mg/L PV and BG. After simulated oral temperature treatment for 30 days, the microstructure of dentin surface was observed by scanning electron microscope (SEM) and the values of surface microhardness (SMH) was measured. Results: The SMH values of group E and F were significantly different from those of other groups(P＜0.01),but there was no significant difference between two groups(P＞0.05). SMH value of group C or D was significantly different from that of group A(P＜0.05). Remineralization were observed in all groups, and the sediments of group E and F were more uniform and tighter. Conclusion: PV can promote the remineralization on the dentin surface, and the combination of PV and BG achieves the synergistic effect.

Key words: phosvitin, remineralization, microhardness, dentin

YU Shaoling, ZANG Ruijue, LI Heng. Regulation of Phosvitin on Remineralization of Demineralized Dentin by Bioactive Glass[J]. Journal of Oral Science Research, 2021, 37(2): 122-125.

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