Journal of Oral Science Research ›› 2020, Vol. 36 ›› Issue (1): 16-19.DOI: 10.13701/j.cnki.kqyxyj.2020.01.005

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Research Status of Cysteine Cathepsinsin Dentine.

WEI Yu, WANG Jun*   

  1. Guangdong Medical University School of Stomatology, Dongguan 523808, China.
  • Received:2019-02-21 Online:2020-01-28 Published:2020-01-16

Abstract: The degradation of dentin matrix collagen is an important factor leading to the destruction of the hybrid layer. Studies have confirmed that the degradation of dentin collagen is closely related to endogenous proteases, such as matrix metalloproteinases (MMPs). In 2010, cysteine cathepsins(CCs, CTs)were firstly detected in dentine, which could degrade collagen fibers. There are more and more studies on cysteine cathepsins at present, this paper will review the research progress on cysteine cathepsins in dentin.

Key words: cystein cathepsins, dentine, adhesive