Clinical and CT Imaging Analysis of Primary Non-Hodgkin Lymphoma of Jaw

doi:10.13701/j.cnki.kqyxyj.2023.11.008

Abstract

Abstract: Objective: To analyze the clinical and CT imaging features of primary bone non-Hodgkin lymphoma (PB-NHL) of jaw retrospectively. Methods: The clinical and CT imaging features of 24 patients with PB-NHL of jaw confirmed by pathology were retrospectively analyzed. Results: Of the 24 patients with PB-NHL of the jaw, 17 were male and 7 were female; 16 underwent anti-inflammatory therapy before diagnosis, 6 underwent tooth extraction, and 2 underwent incision and drainage. In the imaging classification of bone changes, osteolytic type accounted for 17/24, mixed type accounted for 5/24, and alveolar bone resorption accounted for 2/24. In the classification of the edge of bone destruction, moth-eaten destruction margin accounted for 8/24, infiltration destruction margin accounted for 13/24, and geographic type accounted for 3/24. There was significant statistical difference between different parts of mandible and mandible in the classification of bone destruction margin (P=0.003). Moth-eaten was the main type of mandibular edge damage, and infiltration was the main type of maxillary edge damage. Osteolytic type was the most common bone change in posterior mandible. Conclusion: PB-NHL of the jaw has certain clinical and imaging characteristics, which is helpful for the clinical and imaging recognition of the disease.

Key words: jaw, primary non-hodgkin lymphoma, CT imaging, clinical

FENG Yongjing, WEN Shanhui, WANG Tiemei, TENG Yuehui, XIA Shu. Clinical and CT Imaging Analysis of Primary Non-Hodgkin Lymphoma of Jaw[J]. Journal of Oral Science Research, 2023, 39(11): 978-981.

References

[1] Weber MA, Papakonstantinou O, Nikodinovska VV, et al. Ewing's sarcoma and primary osseous lymphoma: Spectrum of imaging appearances[J]. Semin Musculoskelet Radiol, 2019, 23(1):36-57.
[2] Wu H, Zhang L, Shao H, et al. Prognostic significance of soft tissue extension, international prognostic index, and multifocality in primary bone lymphoma: a single institutional experience[J]. Br J Haematol, 2014, 166(1):60-68.
[3] Liu K, Gao Y, Han J, et al. Diffuse large B-cell lymphoma of the mandible diagnosed by metagenomic sequencing: A case report[J]. Front Med (Lausanne), 2021, 8:752523.
[4] Rodrigues-Fernandes CI, de Souza LL, Santos-Costa SFD, et al. Clinicopathological analysis of oral diffuse large B-cell lymphoma, NOS: A systematic review[J]. J Oral Pathol Med, 2019, 48(3):185-191.
[5] Vardas E, Georgaki M, Papadopoulou E, et al. Diagnostic challenges in a diffuse large B-cell lymphoma of the maxilla presenting as exposed necrotic bone[J]. J Clin Exp Dent, 2022, 14(3):e303-e309.
[6] Tazi I, Benmoussa A, Boufarissi FZ, et al. Les lymphomes non-Hodgkiniens osseux de l’adulte[Adult non-Hodgkin bone lymphomas][J]. Bull Cancer, 2021,108(4):424-434.
[7] 潘笑,胡子洋,梁家豪,等.腮腺恶性淋巴瘤的螺旋CT影像表现及分析[J].口腔医学研究,2021,37(7): 651-655.
[8] Mao WY, Lei J, Lim LZ, et al. Comparison of radiographical characteristics and diagnostic accuracy of intraosseous jaw lesions on panoramic radiographs and CBCT[J]. Dentomaxillofac Radiol, 2021, 50(2):20200165.
[9] Shan S, Liu S, Yang ZY, et al. Oral and maxillofacial pain as the first sign of metastasis of an occult primary tumour: A fifteen-year retrospective study[J]. World J Clin Cases, 2022, 10(14):4436-4445.
[10] Caracciolo JT, Temple HT, Letson GD, et al. A modified lodwick-madewell grading system for the evaluation of lytic bone lesions[J]. Am J Roentgenol, 2016, 207(1):150-156.
[11] Michi Y, Harada H, Oikawa Y, et al. Clinical manifestations of diffuse large B-cell lymphoma that exhibits initial symptoms in the maxilla and mandible: a single-center retrospective study[J]. BMC Oral Health, 2022, 22(1):20.
[12] Liu Y, Wang Y, Wang P, et al. A retrospective study to evaluate the CT and MR imaging findings of non-Hodgkin's lymphoma affecting the jaw bones[J]. Oral Radiol, 2022, 38(4):509-516.
[13] Krishnan A, Shirkhoda A, Tehranzadeh J, et al. Primary bone lymphoma: radiographic-MR imaging correlation[J]. Radiographics, 2003, 23(6):1371-1383.
[14] Messina C, Christie D, Zucca E, et al. Primary and secondary bone lymphomas[J]. Cancer Treat Rev, 2015, 41(3):235-246.

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