Journal of Oral Science Research ›› 2024, Vol. 40 ›› Issue (1): 29-34.DOI: 10.13701/j.cnki.kqyxyj.2024.01.006

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Effect of Prophylactic Percutaneous Endoscopic Gastrostomy on Postoperative Infection in Oral Cancer Patients Underwent Radical Resection along with Reconstruction

Parekejiang·PATAER1,2, LI Chenxi1,2,3*, Keremu·ABASI1,2, HU Lulu1,2, FANG Chang1,2, GONG Zhongcheng1,2*   

  1. 1. Department of Oral and Maxillofacial Oncology & Surgery, School/Hospital of Stomatology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China;
    2. Stomatological Research Institute of Xinjiang Uygur Autonomous Region, Urumqi 830054, China;
    3. Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, School of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
  • Received:2023-08-21 Online:2024-01-28 Published:2024-01-22

Abstract: Objective: To investigate the effects of different types of enteral nutrition on surgical site infection after extensive resection and simultaneous reconstruction of patients with oral cancer. Methods: The data of patients who underwent oral cancer radical resection along with reconstruction at Oncological Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Xinjiang Medical University from January 2018 to January 2023 were retrospectively analyzed. According to different enteral nutrition, the patients were divided into the group of prophylactic percutaneous endoscopic gastrostomy (26 cases), group of nasogastric tube (54 cases), and group of oral feeding (33 cases). The changes of postoperative surgical site infection rate and flap necrosis rate among three groups were analyzed through SPSS 25.0 statistical software. Results: The postoperative surgical site infection rate in the group treated with prophylactic percutaneous endoscopic gastrostomy was significantly lower than that in nasogastric tube group and oral feeding group (P<0.05). The rate of flap necrosis had no statistical significance among three groups (P>0.05). The difference of body mass index, total protein, albumin, creatinine, and hematocrit between admission and 6 weeks after surgery was significantly different among three groups (P<0.01). Conclusion: Prophylactic percutaneous endoscopic gastrostomy can effectively reduce the flap infection rate after extensive resection along with simultaneous reconstruction of oral cancer cases, which is worthy of clinical promotion.

Key words: oral cancer, repair and reconstruction, surgical site infection, prophylactic percutaneous endoscopic gastrostomy