Journal of Oral Science Research ›› 2015, Vol. 31 ›› Issue (4): 388-392.

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Meta-analysis of the Relevance between MMP2 Protein and Oral Squamous Cell Carcinoma in China.

ZHU Li-fang, YI An-hua   

  1. The State Key Laboratory Breeding Base of Basic Scienceof Stomatology, Hubei Province & Key Laboraroty of Oral Biomedicine, Ministry of Education, Wuhan University, Wuhan 430079
  • Received:2014-10-23 Online:2015-04-28 Published:2016-04-29

Abstract: Objective: To explore the relevance between MMP2 Protein expression and Oral squamous cell carcinoma in China. Methods: The CNKI, CBM, Wangfang and VIP Database were searched to collect published literature from 1990 to 2014 and meta-analysis was done. Results: 15 publications were finally included in this study. There were 685 cases of OSCC and 275 normal controls. The OR was 13.26, and the 95%CI was 9.02-19.50. Conclusions: Based on research results at present, the high expression of MMP2 protein plays a important role in the development of oral squamous cell carcinoma.

Key words: MMP2 , OSCC , Meta analysis

CLC Number: