Application of Induced Pluripotent Stem Cells (iPSCs) for Dental Tissue Regeneration

Abstract

Abstract: Stem cells can renew themselves by dividing themselves and differentiate into a variety types of cells, so they have important potential applications in regenerative medicine. With the rapid development of tissue engineering, the stem cell-based tooth regenerative will be an important means for replacing the missing and damaged teeth. However, immune rejection and ethical tissues impede the clinical application of these cells. The realization that adult somatic cells can be reprogrammed into pluripotent cells has brought the revolutionary change in dental regeneration. In this review, we will provide a brief introduction to the development of induced pluripotent stem cells and their application in regenerative medicine and dental tissue regeneration.

Key words: Induced pluripotent stem cells, Dental tissue regeneration, Regenerative medicine, Mesenchymal cell

CLC Number:

R782

MA Shan-shan, ZHOU Yan-min, ZHAO Jing-hui, et al. Application of Induced Pluripotent Stem Cells (iPSCs) for Dental Tissue Regeneration[J]. Journal of Oral Science Research, 2015, 31(8): 838-.

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