口腔医学研究 ›› 2021, Vol. 37 ›› Issue (2): 101-104.DOI: 10.13701/j.cnki.kqyxyj.2021.02.002

• 综述 • 上一篇    下一篇

齿龈内阿米巴与牙周炎相关性的研究进展

焦俊玮, 赵蕾*   

  1. 四川大学华西口腔医院牙周科,口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心 四川 成都 610041
  • 收稿日期:2020-04-02 发布日期:2021-02-11
  • 通讯作者: 赵蕾,E-mail:jollyzldoc@163.com
  • 作者简介:焦俊玮(1990~ ),男,山东青岛人,硕士在读,住院医师,研究方向:牙周病学。
  • 基金资助:
    国家自然科学基金(编号:81970944)

Research Progress on Correlation between Entamoeba Gingivalis and Periodontitis

JIAO Junwei, ZHAO Lei*   

  1. Department of Periodontology, West China Hospital of Stomatology, Sichuan University & State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Chengdu 610041, China
  • Received:2020-04-02 Published:2021-02-11

摘要: 齿龈内阿米巴(Entamoeba gingivalis,E.gingivalis)主要出现在人口咽部,是最早被报道的人体阿米巴原虫。E.gingivalis通常存在于口腔卫生状况不良及一些口腔疾病患者,特别是牙周炎患者的牙周袋中具有更高的检出率。尽管通常认为E.gingivalis为共生微生物,但随着检测和分析技术的不断发展,近年来的研究结果表明,该原虫与牙周炎间可能存在更为密切的联系。本文就齿龈内阿米巴与牙周炎相关性的研究进展作一综述。

关键词: 齿龈内阿米巴, 口腔微生物, 牙周炎, 致病机制, 治疗

Abstract: The protozoan Entamoeba gingivalis, commonly resided in the oral cavity and pharynx, is the first described amoeba in human. Entamoeba gingivalis frequently presents a significantly higher prevalence in patients with poor oral hygiene or some oral diseases, especially in the periodontal pockets of periodontitis. Although this species of Entamoeba used to be regarded as a symbiotic microorganism, with the continuous development of detection and analysis techniques, studies in recent years have shown that there may be a close relationship between Entamoeba gingivalis and periodontitis. This article reviews the research progress on the correlation between Entamoeba gingivalis and periodontitis.

Key words: Entamoeba gingivalis, oral microorganism, periodontitis, pathogenic mechanism, treatment