口腔医学研究 ›› 2024, Vol. 40 ›› Issue (8): 749-752.DOI: 10.13701/j.cnki.kqyxyj.2024.08.017

• 研究生病例精粹——口腔黏膜病系列(8) • 上一篇    

妊娠期口腔天疱疮1例

何明靖1,2, 粟缀孜1,3, 周刚1,3*   

  1. 1.口颌系统重建与再生全国重点实验室,口腔生物医学教育部重点实验室,口腔医学湖北省重点实验室,武汉大学口腔医(学)院 湖北 武汉 430079;
    2.武汉大学口腔医院光谷院区牙及牙周疾病诊疗中心 湖北 武汉 430223;
    3.武汉大学口腔医院口腔黏膜科 湖北 武汉 430079
  • 收稿日期:2024-07-18 出版日期:2024-08-28 发布日期:2024-08-22
  • 通讯作者: *周刚,E-mail:zhougang@whu.edu.cn
  • 作者简介:何明靖(1988~ ),女,四川射洪人,博士,主治医师,研究方向:口腔黏膜病学。

Oral Pemphigus during Pregnancy: A Case Report

HE Mingjing1,2, SU Zhuizi1,3, ZHOU Gang1,3*   

  1. 1. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China;
    2. Center for Cariology, Endodontics and Periodontics at Optics Valley Branch. School & Hospital of Stomatology, Wuhan University, Wuhan 430223, China;
    3. Department of Oral Medicine, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2024-07-18 Online:2024-08-28 Published:2024-08-22

摘要: 天疱疮是一类严重的慢性自身免疫性疾病,常表现为皮肤黏膜的薄壁水疱和糜烂。发生于妊娠期的天疱疮少见,可导致不良妊娠结局、新生儿寻常型天疱疮,因此早期诊断及治疗对于母婴健康至关重要。本文报道1例发生于妊娠期的局限于口腔黏膜的天疱疮,探讨该病例的临床表现、诊断、鉴别诊断以及治疗手段,为临床诊疗提供参考。

关键词: 天疱疮, 妊娠期, 诊断, 治疗

Abstract: Pemphigus is a severe and chronic autoimmune blistering disorder that typically presents as cutaneous and mucosal blisters and erosions. Pemphigus in pregnancy is rarely reported and may lead to both maternal and fetal complications, so early diagnosis and management are quite crucial to improve outcomes. Herein, we presented a case of pemphigus during pregnancy with lesions confined to oral cavity. The aim of this report was to explore the clinical manifestations, diagnosis, differential diagnosis, and treatment of this rare condition, and to provide a reference for the clinical diagnosis and treatment of this condition.

Key words: pemphigus, pregnancy, diagnosis, treatment