Abstract: Objective: To design a handpiece surgical guide and to evaluate its clinical effect and accuracy using CBCT technology and 3D printing. Methods: We designed and manufactured handpiece surgical guide with Mimics, Simplant and other softwares. The patients were carried surgery and divided into sleeve guide group (group A) and handpiece guide group (group B). we analyzed the deviation (entry, apical, vertical, and axis)between virtual and actual implants on preoperative and postoperative CBCT data. Results: Ninety-two implants were inserted into 15 patients, including 44 implants for group A and 48 implants for group B. The deviations of entry, apical, vertical, and axis were (0.82 ± 0.47) mm, (0.97 ± 0.47) mm, (0.81 ± 0.43) mm, and (7.89 ± 4.26)°, respectively. According to the analysis of variance, the statistical test found no significant difference in apical, vertical and axis between the two groups. Conclusion: There is no significant difference in accuracy between sleeve guide and handpiece guide. A combination of sleeve guide and handpiece guide is advocated.

Key words: Dental implant, Computer aided design and manufacture , Handpiece surgical guide , 3D printingAccuracy evaluation