Journal of Oral Science Research ›› 2017, Vol. 33 ›› Issue (8): 874-876.DOI: 10.13701/j.cnki.kqyxyj.2017.08.018

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Gingival Lesions Presenting as the First Symptom: Clinicopathologic Characteristics of Gingival non-Hodgkin’s Lymphoma.

SUN Wei-ke1, GONG Xue-mei1, DONG Da-qun1, ZHOU Hui-hui2*.   

  1. 1. School of Stomatology, Binzhou Medical College. Yantai 264003, China;
    2. Department of Pathology, Yuhuangding Hospital affiliated to Qingdao Medical College. Yantai, 264003, China.
  • Received:2017-05-08 Online:2017-08-20 Published:2017-08-28

Abstract: Objective: To investigate the clinicopathologic characteristics and prognosis of gingival non-Hodgkin’s lympahoma (NHL). Methods: Four cases of NHL whose first symptoms were gingival lesions were analyzed. The clinicopathologic and immunohistochemical characteristics were retrospectively studied and the relevant literatures were reviewed. Results: The median age of 4 patients was 59 (43-69). They were 1 male and 3 females. Three cases occurred in maxillary gingival and one case occurred in mandibular gingival. Two cases were diffused large B cell lymphoma (DLBCL), 1 case was anaplastic large cell lymphoma, ALK-negative (ALCL, ALK-negative), and the last one was plasma cell neoplasms. Conclusion: Lymphoma of gingival is very rare and almost NHL, predominated by DLBCL. The diagnosis of gingival lymphoma depends on pathological biopsy. Immunohistochemistry is conducive to diagnosis, typing, and differential diagnosis.

Key words: Gingival lymphoma , Clinical pathological, Immunohistochemistry

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