Journal of Oral Science Research ›› 2019, Vol. 35 ›› Issue (4): 316-318.DOI: 10.13701/j.cnki.kqyxyj.2019.04.002

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Influence Factors of Building Fluorosed Rat Animal Models

TAN Yu-jie, GUO Ling*   

  1. Department of Prosthodontics, Hospital of Stomatology Affiliated to Southwest Medical University, Luzhou 646000, China
  • Received:2018-05-20 Online:2019-04-28 Published:2019-04-23

Abstract: Dental fluorosis is an endemic disease with high incidence rate in China. Rats are widely used for building animal models with dental fluorosis. However, there is no standardized method to set up these models. The present review discusses the methods of building animal models, strains of breeds, gender, age, and weight of rats, with aim to provide a modeling guidance of dental fluorosis.

Key words: Dental fluorosis, Rats, Animal models