Research Progress of Hippo-YAP Signaling Pathway on Inflammation and Regeneration of Periodontal Tissue

doi:10.13701/j.cnki.kqyxyj.2023.01.004

Abstract

Abstract: Periodontitis is a common chronic inflammatory disease, which leads to the progressive destruction of periodontal supporting tissues. On basis of controlling inflammation, striving for a certain degree of periodontal tissue regeneration is the treatment goal of periodontitis. Hippo signaling pathway is a highly conserved signaling pathway, which plays a vital role in mechanical conduction, inflammation, function regulation of stem cells, cell proliferation and differentiation, and tumor occurrence and development. This paper reviews the role of Hippo signaling pathway in periodontal inflammation and periodontal tissue regeneration, in order to provide new inspiration for the treatment of periodontitis.

Key words: periodontitis, Hippo-YAP signaling pathway, periodontal tissue regeneration

ZHAO Huiwei, LIU Shutai. Research Progress of Hippo-YAP Signaling Pathway on Inflammation and Regeneration of Periodontal Tissue[J]. Journal of Oral Science Research, 2023, 39(1): 20-23.

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