Research Progress of Secretion in Mesenchymal Stem Cell-derived Conditioned Medium with Periodontal Regeneration

doi:10.13701/j.cnki.kqyxyj.2021.07.004

Abstract

Abstract: Periodontitis is the leading cause of tooth loss in adults. Rebuilding the defected periodontal tissue and restoring the tooth function are the ideal goal. In recent years, it has been found that the ability of stem cells to induce tissue regeneration is derived from paracrine characteristic. Various biological factors secreted by them exist in the conditioned medium (MSC-CM), exert immune regulation and anti-inflammatory function, regulate cell migration, proliferation, and differentiation, and promote angiogenesis and periodontal tissue repair. This article reviews the basic concepts of MSC-CM and its application for periodontal tissue regeneration.

Key words: mesenchymal stem cells, conditioned medium, periodontal tissue regeneration

ZHOU Xuechun, SUN Xinhua. Research Progress of Secretion in Mesenchymal Stem Cell-derived Conditioned Medium with Periodontal Regeneration[J]. Journal of Oral Science Research, 2021, 37(7): 595-597.

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