Journal of Oral Science Research ›› 2023, Vol. 39 ›› Issue (7): 582-585.DOI: 10.13701/j.cnki.kqyxyj.2023.07.004

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Research Progress in Prevention and Treatment of Biological Agents for Oral Mucositis Caused by Hematopoietic Stem Cell Transplantation

GUO Jincai1,3,4, ZHANG Shusheng2,3*   

  1. 1. Department of Pharmacy, Changsha Stomatological Hospital, Changsha 410006, China;
    2. Changsha Stomatological Hospital, Changsha 410006, China;
    3. School of Stomatology, Hunan University of Chinese Medicine, Changsha 410006, China;
    4. School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
  • Received:2022-07-04 Published:2023-07-25

Abstract: Hematopoietic stem cell transplantation (HSCT) is one of the most important treatment modalities for hematologic malignancies, but this treatment often causes oral mucositis (OM). The incidence of OM caused by HSCT (HSCT-OM) is high and the clinical treatment is difficult. Many biologic agents have been used exploratively in the treatment of HSCT-OM and some are effective. This paper reviews the clinical studies of biologic agents, and provides a reference for the clinical prevention and treatment of HSCT-OM.

Key words: hematopoietic stem cell transplantation, oral mucositis, biological agents