Research on Implantation Accuracy of 3D Printing Individualized Titanium Mesh in Guided Bone Regeneration

doi:10.13701/j.cnki.kqyxyj.2023.10.006

Abstract

Abstract: Objective: To investigate the accuracy of three dimensional printing individualized titanium mesh (3D-PITM) in alveolar bone guided bone regeneration surgery. Methods: CBCT data of 9 patients who underwent guided bone regeneration using 3D-PITM as scaffold material due to severe alveolar bone defects were reconstructed in three dimensions immediately after surgery and 6-9 months after surgery, and the actual titanium mesh was digitally fitted with the preoperative designed titanium mesh model to compare the overall deviation and deformation of the titanium mesh. Results: The average deviation of titanium mesh between immediate post-GBR surgery and preoperative design was (0.76±0.23) mm; between 6-9 months post-GBR surgery and preoperative design was (0.71±0.19) mm; and between 6-9 months post-GBR surgery and immediate post-GBR surgery was (0.35±0.11) mm. The largest deviation value occurred between immediate post-GBR surgery and the preoperative design (3.50 mm). Compared with preoperative design, the largest deformation angle of titanium mesh of immediate post-GBR surgery was 21.49°, the smallest was 0°, and the average was (9.92±8.72)°. The correlation analysis showed that the larger the deformation angle of titanium mesh after GBR surgery, the larger the deviation between it and the preoperative design. Conclusion: The actual position of titanium mesh was still deviated from the preoperative design during 3D-PITM guided bone regeneration. It is necessary to study and improve the accuracy of 3D-PITM guided bone regeneration.

Key words: 3D printing individualized titanium mesh, guided bone generation, accuracy, digital

CHENG Yi, CHEN Gang, ZHAO Pengyu, ZHAO Nan, WANG Chao, CHEN Dan, HUANG Haitao. Research on Implantation Accuracy of 3D Printing Individualized Titanium Mesh in Guided Bone Regeneration[J]. Journal of Oral Science Research, 2023, 39(10): 880-885.

References

[1] Ma H, Feng C, Chang J, et al. 3D-printed bioceramic scaffolds: From bone tissue engineering to tumor therapy [J]. Acta Biomater, 2018, 79:37-59.
[2] Sumida T, Otawa N, Kamata YU, et al. Custom-made titanium devices as membranes for bone augmentation in implant treatment: Clinical application and the comparison with conventional titanium mesh [J]. J Craniomaxillofac Surg, 2015, 43(10):2183-2188.
[3] Ciocca L, Ragazzini S, Fantini M, et al. Work flow for the prosthetic rehabilitation of atrophic patients with a minimal-intervention CAD/CAM approach [J]. J Prosthet Dent, 2015, 114(1):22-26.
[4] Jung GU, Jeon JY, Hwang KG, et al. Preliminary evaluation of a three-dimensional, customized, and preformed titanium mesh in peri-implant alveolar bone regeneration [J]. J Korean Assoc Oral Maxillofac Surg, 2014, 40(4):181-187.
[5] Tallarico M, Park CJ, Lumbau AI, et al. Customized 3D-printed Titanium mesh developed to regenerate a complex bone defect in the aesthetic zone: A case report approached with a fully digital workflow [J]. Materials (Basel), 2020, 13(17):3874.
[6] Xie Y, Li S, Zhang T, et al. Titanium mesh for bone augmentation in oral implantology: current application and progress [J]. Int J Oral Sci, 2020, 12(1): 37.
[7] Cucchi A, Vignudelli E, Franceschi D, et al. Vertical and horizontal ridge augmentation using customized CAD/CAM titanium mesh with versus without resorbable membranes. A randomized clinical trial [J]. Clin Oral Implants Res, 2021, 32(12):1411-1424.
[8] Mian SH, Moiduddin K, Elseufy SM, et al. Adaptive mechanism for designing a personalized cranial implant and its 3D printing using PEEK [J]. Polymers (Basel), 2022, 14(6):1266.
[9] Donos N, Kostopoulos L, Tonetti M, et al. Long-term stability of autogenous bone grafts following combined application with guided bone regeneration [J]. Clin Oral Implants Res, 2005, 16(2):133-139.
[10] Donos N, Kostopoulos L, Karring T. Alveolar ridge augmentation by combining autogenous mandibular bone grafts and non-resorbable membranes [J]. Clin Oral Implants Res, 2002, 13(2):185-191.
[11] Li L, Wang C, Li X, et al. Research on the dimensional accuracy of customized bone augmentation combined with 3D-printing individualized titanium mesh: A retrospective case series study [J]. Clin Implant Dent Relat Res, 2021, 23(1):5-18.
[12] Lizio G, Pellegrino G, Corinaldesi G, et al. Guided bone regeneration using titanium mesh to augment 3-dimensional alveolar defects prior to implant placement. A pilot study [J]. Clin Oral Implants Res, 2022, 33(6):607-621.
[13] Zhang G, Miao X, Lin H, et al. A tooth-supported titanium mesh bending and positioning module for alveolar bone augmentation and improving accuracy [J]. J Esthet Restor Dent, 2023, 35(4):586-595.
[14] 白丽云,季平,李显,等.不同厚度的3D打印个性化钛网的三维有限元分析[J].口腔医学研究,2019,35(1):75-79.
[15] Fokas G, Vaughn VM, Scarfe WC, et al. Accuracy of linear measurements on CBCT images related to presurgical implant treatment planning: A systematic review [J]. Clin Oral Implants Res, 2018, 29 Suppl 16:393-415.
[16] Xie Y, Zeng R, Yan J, et al. Introducing surface-to-surface matching technique to evaluate mandibular symmetry: A retrospective study [J]. Heliyon, 2022, 8(7):e09914.
[17] Lo Giudice A, Ronsivalle V, Grippaudo C, et al. One step before 3D printing-evaluation of imaging software accuracy for 3-dimensional analysis of the mandible: A comparative study using a surface-to-surface matching technique [J]. Materials (Basel), 2020, 13(12):2798.
[18] Otawa N, Sumida T, Kitagaki H, et al. Custom-made titanium devices as membranes for bone augmentation in implant treatment: Modeling accuracy of titanium products constructed with selective laser melting [J]. J Craniomaxillofac Surg, 2015, 43(7):1289-1295.