Journal of Oral Science Research ›› 2024, Vol. 40 ›› Issue (3): 275-278.DOI: 10.13701/j.cnki.kqyxyj.2024.03.017

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Multidisciplinary Diagnosis and Treatment of Extranodal Nasal Type NK/T Cell Lymphoma with Oral Mucosal Ulcer as the First Manifestation: A Case Report

WANG Feng, CHEN Xuya, ZHOU Gang, ZHANG Jing*   

  1. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, Department of Oral Medicine, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2024-02-24 Online:2024-03-28 Published:2024-03-25

Abstract: Extranodal NK/T cell lymphoma, nasal type (ENKTL), is a rare and unique non-Hodgkin's lymphoma that primarily affects the middle face and originates from T cells or NK cells. It is uncommon for cases to present with an oral ulcer as the initial symptom, which can lead to confusion with other diseases and pose challenges for diagnosis. This paper presents a case study on the diagnosis and treatment of Extranodal NK/T-cell lymphoma, nasal type (ENKTL) with initial symptoms of buccal mucosa and gingival ulcer. It analyzes the clinicopathological characteristics, diagnosis, differential diagnosis, and treatment of the disease to offer guidance for clinical management of similar cases.

Key words: extranodal NK/T cell lymphoma, oral ulcer, multidisciplinary diagnosis and treatment