Abstract: Objective:To evaluate the efficacy and respond to adverse reaction of propranolol in the treatment of infantile hemangiomas. Methods:A total of 50 infantile hemangiomas patients aged 1-18m were treated with propranolol at the dosage of 2mg/kg/d. The changes of tumor size, texture and color were monitored and recorded at a regular interval. The adverse effects after medication were observed. The short-term results were evaluated using a Achauer point scale system and color doppler ultrasound B. The adverse effects after medication therapy were observed and managed accordingly. Results:All 50 patients were followed up for 12months, the response was excellent in 11 patients, good in 18, moderate in 17, and poor in 4. There was no statistically significant between sex, race, tumor location and treatment efficacy. There was significantly different between the various type of hemangiomas(P<0.05).There were 16 patients who present various complications after treatment. Conclusion: Propranolol can be safely and effectively used to treat infantile hemangiomas. And no major side-effects were observed. This treatment should be considered as a promising alternative.

Key words: Infantile hemangioma, Propranolol, Efficacy, Side effect