Longitudinal Observation on the Efficacy of Pulsed Nd:YAG Laser with Kangfuxin Solution in the Treatment of Erosive Oral Lichen Planus

Abstract

Abstract: Objective: To evaluate the longitudinal curative effect of pulsed Nd:YAG laser with Kangfuxin solution in the treatment of erosive oral lichen planus (OLP). Methods: An open trial included 121 erosive OLP patients. All patients were randomly divided into three groups: group A (41 patients) was treated with Nd:YAG laser and Kangfuxin solution; group B (40 patients) was treated with Kangfuxin Solution; Group C (40 patients) were treated by local irradiation of Nd:YAG laser. The clinical efficacy was evaluated 24 months after the treatment. Results: There was no significant difference in the recurrent rate between group A, B and C immediate and one month after treatment, however, significant difference in the clinical effective rate (P<0.05). There was a significant difference in both the clinical effective rate and recurrent rate among three groups 6 and 24 months after treatment (P<0.05). Conclusion: Under appropriate irradiation frequency, irradiation angle and exposure time, combination of pulsed Nd:YG laser with Kangfuxin solution has a quick therapeutic effect in the treatment of erosive OLP, with low recurrent rate and high cure rate.

Key words: Nd:YAG lasers, Kangfuxin solution, Erosive oral lichen planus

CLC Number:

R758.65

HU Yuan-yuan, LIU Zong-xiang. Longitudinal Observation on the Efficacy of Pulsed Nd:YAG Laser with Kangfuxin Solution in the Treatment of Erosive Oral Lichen Planus[J]. Journal of Oral Science Research, 2015, 31(9): 907-909.

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