Journal of Oral Science Research

Journal of Oral Science Research ›› 2016, Vol. 32 ›› Issue (8): 861-864.DOI: 10.13701/j.cnki.kqyxyj.2016.08.021

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Curative Effect of Total Glucosides of Paeony Combined with Wolfberry in the Treatment of Olp

Yang1,LIU Si-jia2,CHANG Ying3,WANG Ting-ting3, LI Zheng3, WANG Jing-jiao3,ZHANG Jing3, WANG Li3, QI Ming3*   

  1. 1. Postgraduate Education College, Ningxia Medical University, Yinchuan 750004, China;
    2. School of Stomatology, Ningxia Medical University, Yinchuan 750004, China;
    3. Hospital of Stomatology, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
  • Received:2015-12-14 Online:2016-08-26 Published:2016-08-26

Abstract: Objective: To evaluate the clinical efficacy, the adverse reactions and the changes of the immunity state of OLP patients treated with total glucosides of paeony (TGP) combined with wolfberry. Methods: Seventy OLP patients were randomly divided into two groups: one group with oral TGP capsules and Wolfberry; the other group with oral TGP capsules. The clinical efficacy, the adverse reactions and the changes of the immune function were observed after two months. Results: The total effective rate was 88.57% in the combined group, and the total effective rate was 68.57% in the TGP group. The clinical efficacy was better in the combined group with less adverse reaction (P<0.05). However, the numbers of the C3, C4, CD3+ cells were increased (P<0.05). Conclusion: Per os TGP combined with Wolfberry showed better therapeutic effect, mild adverse reactions, and might regulate the immunity function of OLP patients.

Key words: Total glucosides of paeony, Wolfberry, Immune function, Oral lichen planus

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