Journal of Oral Science Research

Journal of Oral Science Research ›› 2018, Vol. 34 ›› Issue (1): 87-89.DOI: 10.13701/j.cnki.kqyxyj.2018.01.021

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Expression of IL-6 and Shh in Gingival Crevicular Fluid of Patients with Peri-implantitis

CHENG Zhi-fen1, CUI Lian-bao2, XUAN Yan-hua3*   

  1. 1. The First Affiliated Hospital of Zhengzhou University, Stomatological College of Zhengzhou University, Zhengzhou 450001, China;
    2. The Yabaote Dental Clinic, Jinan 250021, China;
    3. Department of Pathology, Yanbian University College of Medicine, Yanji 133000, China.
  • Received:2017-08-10 Online:2018-01-28 Published:2018-01-26

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Abstract: Objective: To study the expression of IL-6 and Shh in patients with peri-implantitis. Methods: Twenty-five patients were included and divided into health implant group (10 cases) and peri-implantitis group (15 cases). The expressions of IL-6 and Shh in health implant group and peri-implantitis group were detected by ELISA assay. Results: The expressions of IL-6 and Shh in the peri-implantitis group were significantly higher than those in the health implant group (P<0.001). There was no positive correlation between IL-6 and Shh (P>0.05). Conclusion: IL-6 and Shh were increased in gingival crevicular fluid of patients with peri-implantitis, and Shh might be a marker to determine the progress of peri-implantitis.

Key words: IL-6, Shh, Peri-implantitis, Gingival crevicular fluid

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