Journal of Oral Science Research ›› 2018, Vol. 34 ›› Issue (5): 474-476.DOI: 10.13701/j.cnki.kqyxyj.2018.05.004

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Influence of Physicochemical Property of Hydrogel on Stem Cell Behavior.

YANG Xue, GAO Hua-li, ZHANG Lu-lu, JIANG Qiu*, Jin Zhi-en, WANG Ting-ting, XU Gao-xiang   

  1. Department of Pediatric Dentistry, Stomatologic Hospital, Jilin University, Changchun 130021, China
  • Received:2017-03-27 Online:2018-05-28 Published:2018-05-29

Abstract: Hydrogel is a kind of high molecular polymer which has a variety of hydrophilic groups and forms three-dimensional network structure. Hydrogel can construct extracellular microenvironment, and provide extracellular matrix for the adhesion, proliferation, differentiation and migration of stem cells. However, the behavior of the stem cells in hydrogel is influenced by many factors. Past researches mainly focused on the effect of biochemical signals on stems cells, however, more and more researchers begin to pay attention to the physicochemical properties of the hydrogel itself. In this paper, the effect of physicochemical properties of hydrogels on the behavior of stem cell was discussed.

Key words: Hydrogel, Chemical property, Physical property, Stem cell behavior