Journal of Oral Science Research ›› 2018, Vol. 34 ›› Issue (7): 793-797.DOI: 10.13701/j.cnki.kqyxyj.2018.07.026

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Cytocompatibility of Pure Magnesium Anodic Oxidation Film after Different Post-treatments

LIU Ji-guang, LI Chong-qian, ZHANG Hui-ming, LI Mu-qin*, SHEN Bai-fang, LIN Ye   

  1. Key Laboratory of Biomedical Materials of Colleges and Universities in Heilongjiang, Jiamusi University, Jiamusi 154007, China.
  • Received:2018-01-04 Online:2018-07-28 Published:2018-07-20

Abstract: Objective: To test the corrosion resistance and cell compatibility of pure magnesium anodic oxidation film after different treatments. Methods: The experiments were divided into pure magnesium anodic oxidation group (group A), pure magnesium anodic oxidation-silane treatment group (group B), pure magnesium anodic oxidation-silane-phytic acid treatment group (group C), pure magnesium anodic oxidation-silane-phytic acid coated copper treatment group (group D). Scanning electron microscopy, laser confocal microscopy, and CCK-8 were used to study the morphology of the films, the cytoskeleton and spreading, and the cell adhesion and proliferation ability of different membranes. Results: The pores of the surface of pure magnesium anodized film were effectively reduced by silane, phytic acid and copper loading, among which, group D>group C>group B>group A. The results of the film surface spreading, adhesion, proliferation of four groups were group C>group D>group B>group A. Conclusion: Pure magnesium anodic oxidation-silane-phytic acid coated copper film has the best sealing ability and good cell activity, and the silane-phytic acid treatment group has the best biological activity.

Key words: Pure magnesium, Anodic oxidation, Silane, Phytic acid, Copper