Research Progress on Relationship between Statins and Periodontitis

doi:10.13701/j.cnki.kqyxyj.2020.09.003

Abstract

Abstract: Statins, which can reduce the formation of cholesterol, are mainly used to treat cardiovascular diseases such as hypercholesterolemia and atherosclerosis. In recent years, studies have found that these drugs have anti-inflammatory, immunomodulatory, antioxidant, and angiogenic effects, and promote the formation of osteoblasts. These characteristics provide great potential for statins to treat chronic inflammatory diseases such as periodontitis. In this paper, the mechanism of statin therapy for periodontitis and related in vivo and in vitro studies are discussed.

Key words: periodontitis, statins, mechanism, progress

LIU Yue, WANG Lei. Research Progress on Relationship between Statins and Periodontitis[J]. Journal of Oral Science Research, 2020, 36(9): 811-813.

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