Journal of Oral Science Research ›› 2021, Vol. 37 ›› Issue (2): 95-100.DOI: 10.13701/j.cnki.kqyxyj.2021.02.001

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Gut Microbiota in Interaction Effects of Periodontitis and Hyperlipidemia

YAN Fuhua*, HUANG Yuezhen   

  1. Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China
  • Received:2020-12-17 Published:2021-02-11

Abstract: Periodontitis and hyperlipidemia are common chronic diseases that seriously affect human health. It is reported that there is a positive relationship between them. However, the exact biological mechanisms are still unclear. Intestinal microecosystem is the largest and most complex ecosystem in human body. Multiple studies have confirmed that the gut microbiota can regulate blood lipids and bone metabolism through its own metabolites, affecting host metabolism and immune response. Both periodontitis and hyperlipidemia can cause changes in the composition of intestinal microbiota. This review aims to deliver an overview of the interaction effects of periodontitis and hyperlipidemia via gut microbiota and provide some new ideas and theoretical bases to improve the recognition of relationship between two diseases.

Key words: periodontitis, hyperlipidemia, gut microbiota